Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Nov 5;21(1):80.
doi: 10.1186/s12981-024-00669-6.

AIDS mortality in Brazil, 2012-2022: a time series study

Lucas de Souza Luna  1 , Rafael Pedro de Souza Nascimento  1 , Paula Esbaltar de Oliveira  1 , Adeilton Gonçalves da Silva Junior  1 , Márcio Bezerra-Santos  2 , Rodrigo José Videres Cordeiro de Brito  1 , Rodrigo Feliciano do Carmo  1 , Carlos Dornels Freire de Souza  3
Affiliations

AIDS mortality in Brazil, 2012-2022: a time series study

Lucas de Souza Luna et al. AIDS Res Ther. .

Abstract

Background: Human immunodeficiency virus (HIV) infection is a health problem in Brazil and worldwide. Without treatment, the infection can progress to Acquired Immunodeficiency Syndrome (AIDS), with a high mortality potential. The objective of this study was to analyze the time trend of AIDS mortality in Brazil, macro-regions, federal units and their respective capitals, from 2012 to 2022.

Methods: This is a time-series study of all AIDS deaths in Brazil from 2012 to 2022. The study included the annual number of deaths and the crude and standardized mortality rates. The Joinpoint regression model was used for the time analysis of the standardized rates. Annual percentage change (APC) and average annual percentage change (AAPC) were calculated. A 95% confidence interval (CI) and a 5% significance level were used.

Results: During the period analyzed, 128,678 AIDS deaths were recorded in Brazil, with a crude mortality rate of 6.3/100,000 and a standardized mortality rate of 5.3/100,000. From 2012 to 2020, three regions showed a declining trend in AIDS mortality: Central-West (AAPC - 2.3%; 95%CI -4.3 to -0.21; p = 0.03), Southeast (AAPC - 5.6%; 95%CI -6.8 to -4.0; p < 0.001), and South (AAPC - 4.4%; 95%CI -5.27 to -3.6; p < 0.001). There was also a downward trend in 10 states and 10 capitals. There was an increase in the number of deaths from 2020 onwards in the North, Northeast and Southeast regions compared to 2019.

Conclusion: There was a downward trend in AIDS mortality from 2012 to 2020 and an upward trend from 2020 to 2022. The regional differences observed could reflect the social disparities that exist in Brazil. In addition, the Covid-19 pandemic has had an impact on the process of dealing with HIV in Brazil.

PubMed Disclaimer

Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Study area. Brazilian States, 2024
Fig. 2
Fig. 2
Time trend of AIDS mortality in Brazil, 2012–2022
Fig. 3
Fig. 3
AIDS mortality rate in Brazilian states, 2012–2022
See this image and copyright information in PMC

Similar articles

See all similar articles

References

    1. World Health Organization. HIV and AIDS. https://www.who.int/news-room/fact-sheets/detail/hiv-aids. Accessed 13 July 2024.
    1. Bekker LG, Beyrer C, Mgodi N, Lewin SR, Delany-Moretlwe S, Taiwo B, Masters MC, Lazarus JV. HIV infection. Nat Rev Dis Primers. 2023;9:42. 10.1038/s41572-023-00452-3. Erratum in: Nat Rev Dis Primers. 2023;9(1):48. 10.1038/s41572-023-00464-z.
    1. World Health Organization. The Global Health Observatory. HIV – Number of new HIV infections. https://www.who.int/data/gho/data/indicators/indicator-details/GHO/numbe.... Accessed 13 July 2024.
    1. Institute for Health Metrics and Evaluation. Global Health Data Exchange (GHDx). https://vizhub.healthdata.org/gbd-results/. Accessed 13 July 2024.
    1. Dian S, Ganiem AR, Ekawardhani S. Cerebral toxoplasmosis in HIV-infected patients: a review. Pathog Glob Health. 2022;117(1):14–23. 10.1080/20477724.2022.2083977. - PMC - PubMed

LinkOut - more resources