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Editorial
. 2024 Sep 4:9:56.
doi: 10.21037/tgh-24-73. eCollection 2024.

KRAS and EGFR inhibitors: a new step in the management of colorectal cancer

Khalil Saleh  1 , Rebecca Ibrahim  1 , Rita Khoury  1 , Zamzam Tikriti  1 , Nadine Khalife  2
Affiliations
Editorial

KRAS and EGFR inhibitors: a new step in the management of colorectal cancer

Khalil Saleh et al. Transl Gastroenterol Hepatol. .
No abstract available

Keywords: KRASG12C mutation; adagrasib; colorectal cancer (CRC); panitumumab; sotorasib.

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Conflict of interest statement

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://tgh.amegroups.com/article/view/10.21037/tgh-24-73/coif). The authors have no conflicts of interest to declare.

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References

    1. Prior IA, Hood FE, Hartley JL. The Frequency of Ras Mutations in Cancer. Cancer Res 2020;80:2969-74. 10.1158/0008-5472.CAN-19-3682 - DOI - PMC - PubMed
    1. Tariq K, Ghias K. Colorectal cancer carcinogenesis: a review of mechanisms. Cancer Biol Med 2016;13:120-35. 10.20892/j.issn.2095-3941.2015.0103 - DOI - PMC - PubMed
    1. Won DD, Lee JI, Lee IK, et al. The prognostic significance of KRAS and BRAF mutation status in Korean colorectal cancer patients. BMC Cancer 2017;17:403. 10.1186/s12885-017-3381-7 - DOI - PMC - PubMed
    1. Neumann J, Zeindl-Eberhart E, Kirchner T, et al. Frequency and type of KRAS mutations in routine diagnostic analysis of metastatic colorectal cancer. Pathol Res Pract 2009;205:858-62. 10.1016/j.prp.2009.07.010 - DOI - PubMed
    1. Pellatt AJ, Bhamidipati D, Subbiah V. Ready, Set, Go: Setting Off on the Mission to Target KRAS in Colorectal Cancer. JCO Oncol Pract 2024;20:1289-92. 10.1200/OP.24.00295 - DOI - PubMed

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