Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2024 Sep 4:9:56.
doi: 10.21037/tgh-24-73. eCollection 2024.

KRAS and EGFR inhibitors: a new step in the management of colorectal cancer

Khalil Saleh  1 , Rebecca Ibrahim  1 , Rita Khoury  1 , Zamzam Tikriti  1 , Nadine Khalife  2
Affiliations
Editorial

KRAS and EGFR inhibitors: a new step in the management of colorectal cancer

Khalil Saleh et al. Transl Gastroenterol Hepatol. .
No abstract available

Keywords: KRASG12C mutation; adagrasib; colorectal cancer (CRC); panitumumab; sotorasib.

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://tgh.amegroups.com/article/view/10.21037/tgh-24-73/coif). The authors have no conflicts of interest to declare.

Comment on

References

    1. Prior IA, Hood FE, Hartley JL. The Frequency of Ras Mutations in Cancer. Cancer Res 2020;80:2969-74. 10.1158/0008-5472.CAN-19-3682 - DOI - PMC - PubMed
    1. Tariq K, Ghias K. Colorectal cancer carcinogenesis: a review of mechanisms. Cancer Biol Med 2016;13:120-35. 10.20892/j.issn.2095-3941.2015.0103 - DOI - PMC - PubMed
    1. Won DD, Lee JI, Lee IK, et al. The prognostic significance of KRAS and BRAF mutation status in Korean colorectal cancer patients. BMC Cancer 2017;17:403. 10.1186/s12885-017-3381-7 - DOI - PMC - PubMed
    1. Neumann J, Zeindl-Eberhart E, Kirchner T, et al. Frequency and type of KRAS mutations in routine diagnostic analysis of metastatic colorectal cancer. Pathol Res Pract 2009;205:858-62. 10.1016/j.prp.2009.07.010 - DOI - PubMed
    1. Pellatt AJ, Bhamidipati D, Subbiah V. Ready, Set, Go: Setting Off on the Mission to Target KRAS in Colorectal Cancer. JCO Oncol Pract 2024;20:1289-92. 10.1200/OP.24.00295 - DOI - PubMed