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. 2025 Feb;24(2):e16668.
doi: 10.1111/jocd.16668. Epub 2024 Nov 6.

Laser and Skin-Care Synergy: A Post-Laser Application of Novel Adaptogenic Moisturizing Serum for Improving Healing and Cosmesis on the Face

Marianna Blyumin-Karasik  1 , Jessica Colon  2 , Sylvie Nguyen  2 , Jordan Rosen  1
Affiliations

Laser and Skin-Care Synergy: A Post-Laser Application of Novel Adaptogenic Moisturizing Serum for Improving Healing and Cosmesis on the Face

Marianna Blyumin-Karasik et al. J Cosmet Dermatol. 2025 Feb.

Abstract

Background: Laser procedures are often used for global improvement in skin quality. The state of the skin is under stress after laser treatment, and it is beneficial to utilize topical agents to assist with optimal healing and cosmetic outcomes. Currently, such post-laser-cosmeceutical synergies are being investigated. Skin adaptogens are bioactive ingredients that enhance the skin's resistance and adaptation to stress.

Aim: Investigate the use of an adaptogenic moisturizing serum (AMS) in synergy with post-laser treatment recovery.

Patient/methods: Eight patients underwent long-pulsed 755-nm alexandrite or 1064-nm picosecond laser treatments on the face, targeting photoaging and pigmentation. After the laser treatment, during their healing process, they utilized a novel AMS twice daily to assist with the post-laser recovery. A blinded expert grader evaluated before and after facial images of each patient using a modified Griffiths photodamage photonumeric scale.

Results: The findings revealed that the AMS was well-tolerated with no reported adverse events, and elicited aesthetically pleasing results. There was a significant decrease in photodamage scores following the treatment (p = 0.0078) with a median reduction of 3.5. Patients had improvement in skin photodamage, pigmentation, and skin radiance in clinic and photography after a combination of laser and AMS serum treatments.

Conclusion: Utilizing the adaptogen moisturizing serum skin care regimen after the laser treatments likely assisted in the skin's healing process. As a result, we propose that there is a potential benefit of combining certain laser treatments and an adaptogen-based skin care regimen for better aesthetic outcomes and skin recuperation post-procedure.

Keywords: aesthetic; cosmeceuticals; healing; homeostasis; laser treatment; moisturizing serum; photoaging; skin adaptogens; skin quality; topical adaptogen.

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Conflict of interest statement

Marianna Blyumin‐Karasik, MD is a founder and CEO of Stamina Beauty, LLC, manufacturer of AMS.

Figures

FIGURE 1
FIGURE 1
Pre/post laser and AMS treatment photos.
FIGURE 2
FIGURE 2
Modified griffiths photodamage photonumeric scale.
See this image and copyright information in PMC

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