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. 2025 Sep 1;20(9):2594-2595.
doi: 10.4103/NRR.NRR-D-24-00659. Epub 2024 Sep 24.

Syndecans in Alzheimer's disease: pathogenetic mechanisms and potential therapeutic targets

Carmela Rita Balistreri  1 , Roberto Monastero  2
Affiliations

Syndecans in Alzheimer's disease: pathogenetic mechanisms and potential therapeutic targets

Carmela Rita Balistreri et al. Neural Regen Res. .
No abstract available

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Figures

Figure 1
Figure 1
New approaches and therapeutic strategies proposed to restore eGCX. Created with BioRender.com. eGCX: Endothelial/glycocalyx; HA: hyaluronic acid; HS: heparan sulfate; NO: nitric oxide; PEG: polyethylene glycol.
See this image and copyright information in PMC

References

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    1. Balistreri CR. Vascular ageing and the related complications in the brain: new insights on related mechanisms and their translational applications. Mech Ageing Dev. 2021;196:111469. - PubMed
    1. Balistreri CR. Promising strategies for preserving adult endothelium health and reversing its dysfunction: from liquid biopsy to new omics technologies and noninvasive circulating biomarkers. Int J Mol Sci. 2022;23:7548. - PMC - PubMed
    1. Balistreri CR, Monastero R. Neuroinflammation and neurodegenerative diseases: how much do we still not know? Brain Sci. 2023;14:19. - PMC - PubMed
    1. Balistreri CR, Di Giorgi L, Monastero R. Focus of endothelial glycocalyx dysfunction in ischemic stroke and Alzheimer’s disease: possible intervention strategies. Ageing Res Rev. 2024;99:102362. - PubMed

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