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. 2024 Nov 7;391(18):1754-1756.
doi: 10.1056/NEJMc2407812.

Simple Strategies to Reduce Cardiac Strain in Older Adults in Extreme Heat

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Simple Strategies to Reduce Cardiac Strain in Older Adults in Extreme Heat

Georgia K Chaseling et al. N Engl J Med. .
No abstract available

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Figures

Figure 1.
Figure 1.. Effect of Cooling Strategies on Heat-Related Cardiac Strain.
Shown are changes from baseline in the rate–pressure product (RPP) with no cooling (control), fan use, skin wetting, and fan use plus skin wetting after exposure for 3 hours to a hot and humid environment (Panel A) or a very hot and dry environment (Panel B) in participants with coronary artery disease (CAD) and those without coronary artery disease. The RPP is calculated as the heart rate in beats per minute (bpm) multiplied by the systolic blood pressure in millimeters of mercury. The hot and humid environment had a temperature of 38.0°C and a relative humidity of 60%. The very hot and dry environment had a temperature of 45.0°C and a relative humidity of 15%. Also shown are mean differences from control in the change from baseline in the RPP with each cooling strategy during exposure for 3 hours to the hot and humid environment (Panel C) or the very hot and dry environment (Panel D) in the overall trial population. Panels in the bottom row show mean differences from control in the change from baseline in the RPP with each cooling strategy during exposure for 3 hours to the hot and humid environment (Panel E) or the very hot and dry environment (Panel F) among participants with coronary artery disease and those without coronary artery disease. The change from baseline in the RPP during exposure to the very hot and dry environment was not assessed for cooling strategies involving fan use in adults with coronary artery disease, owing to safety concerns. I bars indicate 95% confidence intervals (Panels A, B, and D through F) or 98.33% confidence intervals (Panel C). The 95% confidence intervals were not adjusted for multiplicity and should not be used in place of hypothesis testing.

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