Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2024 Oct 20;12(5):99.
doi: 10.21037/atm-24-50. Epub 2024 Sep 5.

Has the CONVINCE trial convinced the nephrology and dialysis community?

Julien Moury  1 , Gauthier Nendumba  1 , Arnaud Robert  1 , Benedicte Hauquiert  1 , Ovidiu Vornicu  1   2 , Sydney Blackman  3 , Emily Perriens  4 , Nathan De Lissnyder  4 , Andriy Shchukin  4 , Farah El Yaakoubi  4 , Clara Saad  4 , Cyril Schmit  4 , Anne-Sophie Dincq  1   2 , Patrick Evrard  1 , Pierre Bulpa  1 , Isabelle Michaux  1 , Patrick M Honore  1
Affiliations
Editorial

Has the CONVINCE trial convinced the nephrology and dialysis community?

Julien Moury et al. Ann Transl Med. .
No abstract available

Keywords: High-flux hemodialysis (HFH); applicability; chronic dialysis patients; high-dose hemodiafiltration; improved prognosis.

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://atm.amegroups.com/article/view/10.21037/atm-24-50/coif). The authors have no conflicts of interest to declare.

Comment on

  • Effect of Hemodiafiltration or Hemodialysis on Mortality in Kidney Failure.
    Blankestijn PJ, Vernooij RWM, Hockham C, Strippoli GFM, Canaud B, Hegbrant J, Barth C, Covic A, Cromm K, Cucui A, Davenport A, Rose M, Török M, Woodward M, Bots ML; CONVINCE Scientific Committee Investigators. Blankestijn PJ, et al. N Engl J Med. 2023 Aug 24;389(8):700-709. doi: 10.1056/NEJMoa2304820. Epub 2023 Jun 16. N Engl J Med. 2023. PMID: 37326323 Clinical Trial.

References

    1. Blankestijn PJ, Vernooij RWM, Hockham C, et al. Effect of Hemodiafiltration or Hemodialysis on Mortality in Kidney Failure. N Engl J Med 2023;389:700-9. 10.1056/NEJMoa2304820 - DOI - PubMed
    1. Drüeke TB, Ikizler TA. Is hemodiafiltration superior to hemodialysis in patients with kidney failure? Kidney Int 2023;104:874-7. 10.1016/j.kint.2023.07.012 - DOI - PubMed
    1. Canaud B, Blankestijn PJ, Grooteman MPC, et al. Why and how high volume hemodiafiltration may reduce cardiovascular mortality in stage 5 chronic kidney disease dialysis patients? A comprehensive literature review on mechanisms involved. Semin Dial 2022;35:117-28. 10.1111/sdi.13039 - DOI - PubMed
    1. Honore PM, Jamez J, Wauthier M, et al. Prospective evaluation of short-term, high-volume isovolemic hemofiltration on the hemodynamic course and outcome in patients with intractable circulatory failure resulting from septic shock. Crit Care Med 2000;28:3581-7. 10.1097/00003246-200011000-00001 - DOI - PubMed
    1. Maduell F, Moreso F, Pons M, et al. High-efficiency postdilution online hemodiafiltration reduces all-cause mortality in hemodialysis patients. J Am Soc Nephrol 2013;24:487-97. 10.1681/ASN.2012080875 - DOI - PMC - PubMed