Rhythmic liver drives feeding behavior

Noelia Martinez-Sanchez^{1

2}, David Ray^{1

2}

Affiliations

¹ National Institute for Health and Care Research Oxford Health Biomedical Research Centre and John Radcliffe Hospital, Oxford, UK.
² Oxford Centre for Diabetes, Endocrinology and Metabolism and Oxford Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK.

Comment

Noelia Martinez-Sanchez et al. Science. 2024.

. 2024 Nov 8;386(6722):622-623.

doi: 10.1126/science.adt0743. Epub 2024 Nov 7.

Noelia Martinez-Sanchez^{1

2}, David Ray^{1

2}

¹ National Institute for Health and Care Research Oxford Health Biomedical Research Centre and John Radcliffe Hospital, Oxford, UK.
² Oxford Centre for Diabetes, Endocrinology and Metabolism and Oxford Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK.

Abstract

The hepatic vagal nerve mediates the impact of circadian disruption on food intake in mice.

Hepatic vagal afferents convey clock-dependent signals to regulate circadian food intake.
Woodie LN, Melink LC, Midha M, de Araújo AM, Geisler CE, Alberto AJ, Krusen BM, Zundell DM, de Lartigue G, Hayes MR, Lazar MA. Woodie LN, et al. Science. 2024 Nov 8;386(6722):673-677. doi: 10.1126/science.adn2786. Epub 2024 Nov 7. Science. 2024. PMID: 39509517