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Case Reports
. 2023 Nov 6;32(3):337-342.
doi: 10.5606/tgkdc.dergisi.2024.24040. eCollection 2024 Jul.

Tracheobronchopathia osteochondroplastica complicated with a pulmonary adenocarcinoma: A rare case report

Zhang Guoliang  1 , Zhang Zefeng  1 , Zhu Qikun  1 , Mi Lili  1 , Wang Rui  1
Affiliations
Case Reports

Tracheobronchopathia osteochondroplastica complicated with a pulmonary adenocarcinoma: A rare case report

Zhang Guoliang et al. Turk Gogus Kalp Damar Cerrahisi Derg. .

Abstract

A 67-year-old female patient presented with a lung nodule one month ago which was detected by physical examination. She was diagnosed with tracheobronchopathia osteochondroplastica complicated with right lower lobe nodules by chest computed tomography, bronchoscopy, and pathological examinations of the biopsy specimens. We performed lobectomy and lymphadenectomy by video-assisted thoracoscopic surgery and small pulmonary lesions were diagnosed as pulmonary adenocarcinomas. At 36 months of follow-up, the patient was free from recurrence. In conclusion, tracheobronchopathia osteochondroplastica complicated with a pulmonary adenocarcinoma is rare, and clinicians should be aware of this possibility, particularly in patients with pulmonary malignancy and tracheal irregularities on chest imaging. Otherwise, tracheobronchopathia osteochondroplastica can be easily misdiagnosed as malignant invasion of the trachea.

Keywords: Pulmonary adenocarcinoma; tracheobronchopathia osteochondroplastica; video-assisted thoracoscopic surgery..

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Conflict of interest statement

Conflict of Interest: The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

Figures

Figure 1
Figure 1. Computed tomography images showing a nodule in about 2.2 cm size in the right lower lobe, presented as burr and pleural traction sign. (a) Lung window, (b) mediastinal window.
Figure 2
Figure 2. Computed tomography images showing calcifications on the anterior and lateral walls of the trachea that extended from the origin of the trachea to the carina (arrow). (a and c) Lung window, (b and d) Mediastinal window.
Figure 3
Figure 3. (a, b) Bronchoscopy showing multiple protruding sessile nodules covered with the anterior and lateral walls of trachea without any obvious endobronchial lesions.
Figure 4
Figure 4. Histopathological findings. (a) Tracheobronchopathia osteochondroplastica illustrate submucosal ossification and cartilage formation, accompanied by a number of inflammatory cells (H&E, ×400). (b) The lower lobe nodules of the right were invasive adenocarcinomas with 90% of acini and 10% micropapillary (H&E, ×400).
See this image and copyright information in PMC

References

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