Inhibitors of the Interleukin-1 Receptor Accessory Protein Signaling: Another Asset in the Cardio-Immunology Toolbox
- PMID: 39513252
- PMCID: PMC11652230
- DOI: 10.1161/CIRCHEARTFAILURE.124.012244
Inhibitors of the Interleukin-1 Receptor Accessory Protein Signaling: Another Asset in the Cardio-Immunology Toolbox
Keywords: Editorials; immune system; immunity; inflammation; myocarditis.
Conflict of interest statement
Dr Toldo reports consultant fees from CardiolRx. Dr Abbate reports advisory panel/consultant fees from CardiolRx, Kiniksa, and Novo Nordisk. The other author reports no conflicts.
Comment on
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IL1RAP Blockade With a Monoclonal Antibody Reduces Cardiac Inflammation and Preserves Heart Function in Viral and Autoimmune Myocarditis.Circ Heart Fail. 2024 Dec;17(12):e011729. doi: 10.1161/CIRCHEARTFAILURE.124.011729. Epub 2024 Nov 8. Circ Heart Fail. 2024. PMID: 39513273 Free PMC article.
References
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- Toldo S et al. Formation of the inflammasome in acute myocarditis. Int. J. Cardiol. 171, e119–121 (2014). - PubMed
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- Kraft L, Erdenesukh T, Sauter M, Tschöpe C & Klingel K Blocking the IL-1β signalling pathway prevents chronic viral myocarditis and cardiac remodeling. Basic Res. Cardiol. 114, 11 (2019). - PubMed
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