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. 2025 May 1;34(3):264-266.
doi: 10.1097/CEJ.0000000000000936. Epub 2024 Nov 6.

Cryoablation of early breast cancer: the challenge towards de-escalation of surgical treatment

Mattia Intra  1 , Francesca Magnoni  1 , Paolo Della Vigna  2 , Luca Nicosia  3 , Giovanni Mazzarol  4 , Viviana Galimberti  1 , Franco Orsi  2 , Paolo Veronesi  1   5
Affiliations

Cryoablation of early breast cancer: the challenge towards de-escalation of surgical treatment

Mattia Intra et al. Eur J Cancer Prev. .
No abstract available

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References

    1. Fine RE, Gilmore RC, Dietz JR, Boolbol SK, Berry MP, Han LK, et al. (2021). Cryoablation without excision for low-risk early-stage breast cancer: 3-year interim analysis of ipsilateral breast tumor recurrence in the ICE3 trial. Ann Surg Oncol 28:5525–5534.
    1. Gentilini OD, Botteri E, Sangalli C, Galimberti V, Porpiglia M, Agresti R, et al.; SOUND Trial Group (2023). Sentinel lymph node biopsy vs no axillary surgery in patients with small breast cancer and negative results on ultrasonography of axillary lymph nodes: the SOUND randomized clinical trial. JAMA Oncol 9:1557–1564.
    1. Jatoi I, Kunkler IH (2021). Omission of sentinel node biopsy for breast cancer: historical context and future perspectives on a modern controversy. Cancer 127:4376–4383.
    1. Kawamoto H, Tsugawa K, Furuya Y, Sakamaki K, Kakimoto S, Kitajima M, et al. (2024). Percutaneous ultrasound-guided cryoablation for early-stage primary breast cancer: a follow-up study in Japan. Breast Cancer 31:695–704.
    1. Khan S, Cole J, Habrawi Z, Melkus M, Rahman RL (2023). Cryoablation allows the ultimate de-escalation of surgical therapy in select breast cancer patients. Ann Surg Oncol 30:8398–8403.

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