Rapid growth of acquired UBA1 mutations predisposes male patients to low-risk MDS

Peng Li^{1

2}, F N U Alnoor^{3

4}, Wei Xie⁵, Margaret Williams^{3

6}, Julie Feusier^{3

6}, Yi Ding⁷, Xiangrong Zhao⁸, Gang Zheng⁹, Chen Zhao¹⁰, Arthur W Zieske¹¹, Youli Zu¹¹, Philipp W Raess⁵, Srinivas Tantravahi^{12

13}, Afaf Osman^{12

13}, Ami B Patel^{12

13}, Tsewang Tashi^{12

13}, Jay L Patel^{3

6}, Anna P Matynia^{3

6}, Madhu P Menon^{3

6}, Rodney R Miles^{3

6

13}, Jeffrey R Jacobsen^{3

6}, Tracy I George^{3

6

13}, Douglas W Sborov^{12

13}, Philippe Szankasi⁶, Paul Rindler⁶, Devin Close⁶, Robert S Ohgami^{3

6}

Affiliations

¹ Department of Pathology, University of Utah Health, Salt Lake City, UT, USA. peng.li@hsc.utah.edu.
² ARUP Laboratories, Salt Lake City, UT, USA. peng.li@hsc.utah.edu.
³ Department of Pathology, University of Utah Health, Salt Lake City, UT, USA.
⁴ Department of Pathology & Immunology, Washington University, St. Louis, MO, USA.
⁵ Department of Pathology and Laboratory Medicine, School of Medicine, Oregon Health & Science University, Portland, OR, USA.
⁶ ARUP Laboratories, Salt Lake City, UT, USA.
⁷ Laboratory Medicine, Geisinger Medical Center, Danville, PA, USA.
⁸ Kaiser Permanente Sacramento Medical Center, Sacramento, CA, USA.
⁹ Mayo Clinic Laboratories, Rochester, MN, USA.
¹⁰ Department of Pathology and Laboratory Medicine, Case Western Reserve University, Cleveland, OH, USA.
¹¹ Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, TX, USA.
¹² Department of Internal Medicine, University of Utah Health, Salt Lake City, UT, USA.
¹³ Huntsman Cancer Institute, Salt Lake City, UT, USA.

Peng Li et al. Leukemia. 2025 Jan.

. 2025 Jan;39(1):248-256.

doi: 10.1038/s41375-024-02397-2. Epub 2024 Nov 8.

¹ Department of Pathology, University of Utah Health, Salt Lake City, UT, USA. peng.li@hsc.utah.edu.
² ARUP Laboratories, Salt Lake City, UT, USA. peng.li@hsc.utah.edu.
³ Department of Pathology, University of Utah Health, Salt Lake City, UT, USA.
⁴ Department of Pathology & Immunology, Washington University, St. Louis, MO, USA.
⁵ Department of Pathology and Laboratory Medicine, School of Medicine, Oregon Health & Science University, Portland, OR, USA.
⁶ ARUP Laboratories, Salt Lake City, UT, USA.
⁷ Laboratory Medicine, Geisinger Medical Center, Danville, PA, USA.
⁸ Kaiser Permanente Sacramento Medical Center, Sacramento, CA, USA.
⁹ Mayo Clinic Laboratories, Rochester, MN, USA.
¹⁰ Department of Pathology and Laboratory Medicine, Case Western Reserve University, Cleveland, OH, USA.
¹¹ Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, TX, USA.
¹² Department of Internal Medicine, University of Utah Health, Salt Lake City, UT, USA.
¹³ Huntsman Cancer Institute, Salt Lake City, UT, USA.

No abstract available

Conflict of interest statement

Competing interests: The authors declare no competing interests.

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