Incidence of post-intensive care syndrome among patients admitted to post-ICU multidisciplinary consultations: the retrospective observational PICS-MIR study

Abstract

To determine the prevalence of functional, respiratory and renal impairments and of post-intensive-care-syndrome (PICS) among patients who had attended a post-ICU multidisciplinary consultation (post-ICU-MC) around 3 months after ICU discharge, we performed a retrospective, monocentric observational study, at Clermont Ferrand University hospital, France. We included patients who had attended a post-ICU-MC. Their characteristics during ICU stay and at the post-ICU-MC were collected. Functional status was assessed by the 6-min-walking test, handgrip test and peak inspiratory pressure, respiratory function by exploratory functional outcomes, mental status by SF-36 score, and quality of life by SF-36 score and European Quality of Life 5 Dimensions questionnaire. Overall, we enrolled 67 patients, of whom 70%, 74%, and 68% had functional, respiratory, and renal impairments, respectively, at the post-ICU-MC. Additionally, 40%, 28%, 19%, and 2.5% had three, two, one, and none of these impairments, respectively. All patients experienced mental disorders and a decline in quality of life. Functional impairment correlated with frailty score and sex, and respiratory function with age. To conclude, the prevalence of PICS in our cohort was high, as was that of functional, respiratory and renal failure.

Keywords: Intensive care; Long term outcomes; Multidisciplinary consultations.

Fig. 1

Flow chart. Post ICU MC: post intensive care multidisciplinary consultations; ICU LOS: intensive care unit length of stay.

Fig. 2

Distribution of the patients depending on their place of residence, functional status and frailty score before ICU and at the post-ICU multidisciplinary consultations. ICU: Intensive care unit; Post-ICU-MC: post intensive care multidisciplinary consultations.

Fig. 3

Venn diagram of the population according to functional, respiratory and renal impairment.

Fig. 4

Correlation between parameters during ICU stay and during post-ICU-Multidisciplinary consultations. PCS = Physical summary score of the Short Form 36; PIP = Peak inspiratory pressure; HGT = handgrip test; ICU = intensive care unit; LOS = length of stay; GFR = glomerular filtration rate; MCS = Psychological summary score of the Short Form 36; SAPS II = Simplified acute physiology score.