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. 2025 Aug;81(8):4667-4680.
doi: 10.1111/jan.16607. Epub 2024 Nov 11.

Clinical Factors Affecting the Quality of Life of Women With Endometriosis

Agnieszka Bień  1 , Aleksandra Pokropska  2 , Joanna Grzesik-Gąsior  3 , Magdalena Korżyńska-Piętas  1 , Marta Zarajczyk  1 , Ewa Rzońca  4 , Krzysztof Jurek  5
Affiliations

Clinical Factors Affecting the Quality of Life of Women With Endometriosis

Agnieszka Bień et al. J Adv Nurs. 2025 Aug.

Abstract

Aim: The study aimed to analyse selected clinical data affecting the quality of life of women with endometriosis.

Design: A cross-sectional study.

Method: The study was conducted in 2020-2022 among 425 women with endometriosis receiving health care. A diagnostic survey method with a questionnaire technique was used. The research tools are the Endometriosis Health Profile and a standardised interview questionnaire.

Results: Infertility, medical treatment and sexual intercourse were the dimensions of quality of life most poorly rated by respondents with endometriosis. Lower quality of life was linked to the presence of painful periods, the presence of pain during intercourse and having surgery for endometriosis.

Conclusion: The main clinical variables influencing the quality of life of women with endometriosis include problems with getting pregnant, the necessity for long-term therapy and sexual problems caused by the condition. The occurrence of painful menstruation, dyspareunia and having undergone surgery for endometriosis is associated with lower ratings of women's general quality of life.

Implications for the profession: The study will help to develop a more holistic approach to caring for endometriosis patients. This will result in a better diagnosis, individualised therapy and psychological support, all of which will enhance the overall quality of life. The study's results may impact the development of health policies, endometriosis support services for women and public awareness initiatives.

Impact: The study highlighted key determinants affecting health-related quality of life for women with endometriosis. The analysis of clinical data revealed that infertility, treatment and dyspareunia are the dimensions of quality of life most poorly rated by women with endometriosis. These findings are significant for those providing care to women with endometriosis, as well as for policymakers responsible for the organisation of health care systems.

Reporting method: The STROBE guidelines.

Patient or public contribution: No patient or public contribution.

Keywords: clinical factors; endometriosis; midwifery; nursing; obstetrics and gynaecology; quality of life; reproductive health; women's health.

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Conflict of interest statement

The authors declare no conflicts of interest.

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