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Randomized Controlled Trial
. 2024 Dec;10(6):e70026.
doi: 10.1002/cre2.70026.

Clinical and Patient-Reported Outcome Measures of Palatal Donor Site Healing Using Polyvinylpyrrolidone-Sodium Hyaluronate Gel as a Dressing Material Following Free Gingival Graft Harvesting: A Randomized Controlled Clinical Trial

Mohammad Baroudi  1 , Majd Othman  1
Affiliations
Randomized Controlled Trial

Clinical and Patient-Reported Outcome Measures of Palatal Donor Site Healing Using Polyvinylpyrrolidone-Sodium Hyaluronate Gel as a Dressing Material Following Free Gingival Graft Harvesting: A Randomized Controlled Clinical Trial

Mohammad Baroudi et al. Clin Exp Dent Res. 2024 Dec.

Abstract

Objectives: This study evaluates the efficacy of polyvinylpyrrolidone-sodium hyaluronate (PVP-SH) gel as a dressing material in enhancing both clinical and patient-reported outcomes post-free gingival graft (FGG) harvesting from the hard palate.

Material and methods: This randomized clinical trial included 18 patients and spanned from June 2022 to August 2023. Patients received an FGG procedure to manage a lack of attached gingiva. Following graft harvesting, patients were divided into two groups: the control group, which received Coe-Pak, and the test group, which was treated with PVP-SH gel. The primary outcome measured was complete epithelialization. Secondary outcomes included the Landry healing scale, post-operative pain level, and patient willingness to receive the same treatment again.

Results: The test group reported significantly lower analgesic use (p < 0.001) and reduced pain severity (p < 0.001) compared to the control group. Furthermore, test group patients indicated a higher level of satisfaction regarding the prospect of retreatment. In contrast, the control group showed significantly slower progress in wound healing and epithelization (p < 0.05) compared to the test group.

Conclusions: The findings of this study suggest that PVP-SH gel is a superior dressing material post-FGG harvesting, yielding improved clinical and patient-reported outcomes relative to Coe-Pak.

Keywords: pain; palate; wound healing.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
The harvesting and measurements of length, width, and thickness of the graft.
Figure 2
Figure 2
The application of Coe‐Pak dressing to the palatal donor site.
Figure 3
Figure 3
The application of PVP‐SH gel to the inside of the stent.
Figure 4
Figure 4
CONSORT flow diagram.
See this image and copyright information in PMC

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