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. 2024 Oct;30(14):13-18.
doi: 10.3201/eid3014.240306.

Next-Generation Sequencing and Bioinformatics Consortium Approach to Genomic Surveillance

Lindsay C Morton, Nazia Rahman, Kimberly A Bishop-Lilly

Next-Generation Sequencing and Bioinformatics Consortium Approach to Genomic Surveillance

Lindsay C Morton et al. Emerg Infect Dis. 2024 Oct.

Abstract

Genomic surveillance programs benefit greatly from a network of committed, well-supported laboratories that conduct ongoing surveillance activities for pathogens of public health importance. The experiences of the Global Emerging Infections Surveillance program provide insights for building and maintaining genomic surveillance capabilities for public health and pandemic preparedness and response. To meet the needs of US Department of Defense and the Military Health System to use genomics to monitor pathogens of military and public health importance, Global Emerging Infections Surveillance convened a consortium of experts in genome sequencing, bioinformatics, and genomic epidemiology. The experts developed a 3-tiered framework for building and maintaining next-generation sequencing and bioinformatics capabilities for genomic surveillance within the Department of Defense. The consortium strategy was developed before the COVID-19 pandemic, leading to a network prepared to respond with existing resources and expand as new funding became available.

Keywords: GEIS; Genomic surveillance. Global Emerging Infections Surveillance; Next-Generation Sequencing and Bioinformatics Consortium; bioinformatics; consortium; sequencing.

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Figure
Tiered sequencing and bioinformatics capabilities for genomic surveillance within the US DoD. Modified from (15). DoD, Department of Defense; GEIS, Global Emerging Infections Surveillance.
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