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. 2024 Nov 4;7(11):e2444540.
doi: 10.1001/jamanetworkopen.2024.44540.

Patient-Reported Discussions on Fertility Preservation Before Early-Onset Cancer Treatment

Samantha R Keller  1 , Allison Rosen  2 , Mark A Lewis  3 , Hyo K Park  4 , Rebecca Babyak  1 , Jill Feldman  5 , Fei Ye  6   7 , Rajiv Agarwal  1   7 , Kristen K Ciombor  1   7 , Timothy M Geiger  8 , Cathy Eng  1   7 , Katherine J Hunzinger  9 , Richard H Viskochil  10 , Michelle K Roach  7 , Digna R Velez Edwards  11 , Michele L Cote  12 , Andreana N Holowatyj  1   7   13
Affiliations

Patient-Reported Discussions on Fertility Preservation Before Early-Onset Cancer Treatment

Samantha R Keller et al. JAMA Netw Open. .
No abstract available

Plain language summary

This cross-sectional study evaluates discussion patterns about fertility preservation options reported by patients with early-onset cancer to better understand the patient experience.

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Conflict of interest statement

Conflict of Interest Disclosures: Dr Holowatyj is Chair of the Scientific Advisory Board for the Appendix Cancer Pseudomyxoma Peritonei (ACPMP) Research Foundation and reports receiving grants from the American Cancer Society and National Institutes of Health (NIH) for the conduct of this study and receiving grants from the ACPMP Research Foundation, Dalton Family Foundation, and Pfizer, Inc outside the submitted work. Dr Holowatyj also reports personal fees from MJH Life Sciences and Bayer AG outside the submitted work. Dr Ciombor reports Consultant/Advisory Board participation for Merck, Pfizer, Lilly/Loxo, Seagen, Personalis, Replimune, Incyte, and Exelixis and receiving grants from BMS, Array, Incyte, Daiichi Sankyo, Nucana, Merck, Pfizer/Calithera, Genentech, and Seagen. No other disclosures were reported.

Figures

Figure.
Figure.. Patterns of Patient-Reported Discussions on Fertility Preservation by Cancer Site (REACT [Reproductive Health After Cancer Diagnosis & Treatment] Study)
Proportions of patients across early-onset cancer sites who reported having had a discussion on fertility preservation before treatment initiation. aCancer sites each with fewer than 10 total cases were included in the other cancers group. These sites include anus, anal canal, and anorectum; appendix; bones and joints; esophagus; kidney and renal pelvis; liver and intrahepatic bile duct; melanoma (skin); myeloma; pancreas; prostate; salivary glands; soft tissue; urinary bladder; vulva; other nervous system; head and neck; stomach; and gastrointestinal stromal tumors. bColorectum excludes appendiceal cancers.
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References

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