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Meta-Analysis
. 2024 Nov 8;103(45):e40439.
doi: 10.1097/MD.0000000000040439.

The effect of psychological intervention on the quality of life and rehabilitation outcome of stroke patients with anxiety and depression: A systematic review

Affiliations
Meta-Analysis

The effect of psychological intervention on the quality of life and rehabilitation outcome of stroke patients with anxiety and depression: A systematic review

Bingquan Zhao et al. Medicine (Baltimore). .

Abstract

Background: To systematically evaluate the effects of psychological interventions on the quality of life and rehabilitation efficacy of patients with poststroke anxiety and poststroke depression.

Methods: All randomized controlled trials of psychological interventions for the treatment of patients with poststroke anxiety combined with poststroke depression in China National Knowledge Infrastructure, Wan Fang Database, the Chongqing VIP Chinese Science and Technology Periodical Database (VIP), Chinese Biomedical Literature Database, Cochrane Library, Embase, Web of Science, and PubMed were searched. Literature was screened according to inclusion and exclusion criteria, systematic evaluation, and meta-analysis were performed using revman5.0 software.

Results: Seventeen randomized controlled trials were included, which showed that the psychological intervention group was more effective than the control group in reducing anxiety and depression and improving patients' ability to perform daily life and quality of life. Subgroup analyses were performed according to intervention time and assessment scale, and the results showed that the intervention group was more effective in reducing anxiety and depression.

Conclusion: Psychological interventions can improve the ability of patients with stroke combined with anxiety and depression to perform their daily lives, improve their quality of life, reduce their levels of depression and anxiety, and improve functional impairment. The registration number in PROSPERO is CRD42023325594 (http://www.crd.york.ac.uk/PROSPERO/).

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

Figures

Figure 1.
Figure 1.
PRISMA flow diagram of search results.
Figure 2.
Figure 2.
Risk of bias graph.
Figure 3.
Figure 3.
Risk of bias summary.
Figure 4.
Figure 4.
Effect of psychological interventions on anxiety.
Figure 5.
Figure 5.
Effect of psychological intervention on anxious patients (subgroup analysis according to intervention time).
Figure 6.
Figure 6.
Effect of psychological interventions on anxiety (subgroup analysis based on assessment scales).
Figure 7.
Figure 7.
Effect of psychological interventions on depression.
Figure 8.
Figure 8.
Effect of psychological interventions on depression (subgroup analysis according to intervention time).
Figure 9.
Figure 9.
Effect of psychological interventions on depression (subgroup analysis based on assessment measures).
Figure 10.
Figure 10.
Effect of psychological intervention on daily living ability score (Barthel index) in patients with stroke combined with depression and anxiety.
Figure 11.
Figure 11.
Effect of psychological intervention on quality of life scores (QOL scale) in patients with stroke combined with depression and anxiety.

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