Insulin-Related Suicides-3 Cases
- PMID: 39534452
- PMCID: PMC11552034
- DOI: 10.1177/19253621241272228
Insulin-Related Suicides-3 Cases
Abstract
Insulin is a pancreas-produced hormone, which is essential for normal life. In persons with diabetes, who lack sufficient production of endogenous insulin, the availability of exogenously-produced and administered insulin represents an extremely valuable, life-preserving medical advancement. Unfortunately, as with many other medications, overdosage with insulin can and does occur, sometimes in an intentional suicidal manner. Another possible insulin-related suicidal action involves the intentional cessation of insulin therapy by someone who relies on insulin for survival. In this case series, we present 3 cases of insulin-related suicides, including two related to intentional insulin overdose and one where a known diabetic purposefully stopped taking insulin in order to commit suicide.
Keywords: Forensic pathology; diabetes; insulin; intentional medication withdrawal; medication cessation; overdose; suicide.
© The Author(s) 2024.
Conflict of interest statement
This paper was presented at the 2022 National Association of Medical Examiners Annual Meeting. The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
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References
-
- Roberge RJ, Martin TG, Delbridge TR. Intentional massive insulin overdose: recognition and management. Ann Emerg Med. 1993;22(2):228–234. - PubMed
-
- Winston DC. Suicide via insulin overdose in nondiabetics: the New Mexico experience. Am J Forensic Med Pathol. 2000;21(3):237–240. - PubMed
-
- Haibach H, Dix JD, Shah JH. Homicide by insulin administration. J Forensic Sci. 1987;32(1):208–216. - PubMed
-
- Hood I, Mirchandani H, Monforte J, Stacer W. Immunohistochemical demonstration of homicidal insulin injection site. Arch Pathol Lab Med. 1986;110(10):973–974. - PubMed
-
- Corey TS, Weakly-Jones B, Nichols GR, II, Theuer HH. Unnatural deaths in nursing home patients. J Forensic Sci. 1992;37(1):222–227. - PubMed
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