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Review
. 2024 Nov-Dec;31(6):e70004.
doi: 10.1111/xen.70004.

Ethical Implications of Social Science Research on Xenotransplantation

Johannes Kögel  1 , Paulina Ernst  2 , Jochen Sauermeister  2 , Georg Marckmann  1
Affiliations
Review

Ethical Implications of Social Science Research on Xenotransplantation

Johannes Kögel et al. Xenotransplantation. 2024 Nov-Dec.

Abstract

Social science research has generated extensive knowledge on xenotransplantation, encompassing the perspectives of actual and potential patients, other stakeholders, public opinion and debate, human-animal relationships, animal production and husbandry, bioeconomy, as well as biotechnology governance and regulation. We therefore convened social science researchers to discuss the latest developments in xenotransplantation research and practice in late 2023. Based on a brief workshop report, we aim to highlight the various ethical implications of this debate. After outlining the role of social science research in the ethical evaluation of xenotransplantation, we elaborate three critical points that may become pivotal in the future evolution of xenotransplantation: the framing of xenotransplantation in the clinical setting and in the public, the potential impact of religious beliefs on patients' transplant choices, and the consequences for the allotransplantation system if xenotransplantation becomes clinically established, including the allocation of allo- and xeno-organs.

Keywords: allocation; ethics; framing; religion; social sciences; xenotransplantation.

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