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Review
. 2025 Feb;73(1):8-22.
doi: 10.23736/S2724-5683.24.06288-4. Epub 2024 Nov 13.

Applications and potential of machine, learning augmented chest X-ray interpretation in cardiology

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Review

Applications and potential of machine, learning augmented chest X-ray interpretation in cardiology

Michael R Milne et al. Minerva Cardiol Angiol. 2025 Feb.

Abstract

The chest X-ray (CXR) has a wide range of clinical indications in the field of cardiology, from the assessment of acute pathology to disease surveillance and screening. Despite many technological advancements, CXR interpretation error rates have remained constant for decades. The application of machine learning has the potential to substantially improve clinical workflow efficiency, pathology detection accuracy, error rates and clinical decision making in cardiology. To date, machine learning has been developed to improve image processing, facilitate pathology detection, optimize the clinical workflow, and facilitate risk stratification. This review explores the current and potential future applications of machine learning for chest radiography to facilitate clinical decision making in cardiology. It maps the current state of the science and considers additional potential use cases from the perspective of clinicians and technologists actively engaged in the development and deployment of deep learning driven clinical decision support systems.

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