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. 1986 Mar;38(3):395-9.

Aldehyde dehydrogenase polymorphism in North American, South American, and Mexican Indian populations

H W Goedde, D P Agarwal, S Harada, F Rothhammer, J O Whittaker, R Lisker

Aldehyde dehydrogenase polymorphism in North American, South American, and Mexican Indian populations

H W Goedde et al. Am J Hum Genet. 1986 Mar.

Abstract

While about 40% of the South American Indian populations (Atacameños, Mapuche, Shuara) were found to be deficient in aldehyde dehydrogenase isozyme I (ALDH2 or E2), preliminary investigations showed very low incidence of isozyme deficiency among North American natives (Sioux, Navajo) and Mexican Indians (mestizo). Possible implications of such trait differences on cross-cultural behavioral response to alcohol drinking are discussed.

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