Case Reports
doi: 10.1002/ajmg.1320230129.
Autism in fragile X females
- PMID: 3953655
- DOI: 10.1002/ajmg.1320230129
Item in Clipboard
Case Reports
Autism in fragile X females
Am J Med Genet.
1986 Jan-Feb.
Abstract
We present two women with the fragile X syndrome (Martin-Bell syndrome) and autism. Both are mentally retarded, one mildly and one severely. Cytogenetic studies showed a high percentage of lymphocytes with the fragile X chromosome and inactivation occurring preferentially in the normal X chromosome. Autism is shown to be a severe behavioral and cognitive manifestation of the fragile X syndrome in females.
Similar articles
-
Infantile autism: an occasional manifestation of fragile (X) mental retardation.Am J Med Genet. 1986 Jan-Feb;23(1-2):353-8. doi: 10.1002/ajmg.1320230127. Am J Med Genet. 1986. PMID: 3953653
-
Infantile autism and the fragile X. A Swedish multicenter study.Am J Med Genet. 1986 Jan-Feb;23(1-2):403-8. doi: 10.1002/ajmg.1320230132. Am J Med Genet. 1986. PMID: 3953658
-
Autism is associated with the fragile-X syndrome.J Autism Dev Disord. 1982 Sep;12(3):303-8. doi: 10.1007/BF01531375. J Autism Dev Disord. 1982. PMID: 7153204 No abstract available.
-
Fragile X and autism: a multicenter survey.Am J Med Genet. 1986 Jan-Feb;23(1-2):341-52. doi: 10.1002/ajmg.1320230126. Am J Med Genet. 1986. PMID: 3513570 Review.
-
[Autism and fragile X syndrome. Pedopsychiatric aspects].Arch Fr Pediatr. 1989 Mar;46(3):211-6. Arch Fr Pediatr. 1989. PMID: 2660769 Review. French. No abstract available.
Cited by
-
Role of Genetics in the Etiology of Autistic Spectrum Disorder: Towards a Hierarchical Diagnostic Strategy.Int J Mol Sci. 2017 Mar 12;18(3):618. doi: 10.3390/ijms18030618. Int J Mol Sci. 2017. PMID: 28287497 Free PMC article. Review.
-
Fragile X in female autistic twins.J Autism Dev Disord. 1988 Sep;18(3):458-60. doi: 10.1007/BF02212201. J Autism Dev Disord. 1988. PMID: 3170462 No abstract available.
-
Neuroanatomy in fragile X females: the posterior fossa.Am J Hum Genet. 1991 Aug;49(2):279-88. Am J Hum Genet. 1991. PMID: 1867191 Free PMC article.
-
Fragile X syndrome. Molecular and clinical insights and treatment issues.West J Med. 1997 Feb;166(2):129-37. West J Med. 1997. PMID: 9109330 Free PMC article. Review.
-
Brain-Derived Neurotrophic Factor in children with Autism Spectrum Disorder.Ann Neurosci. 2014 Oct;21(4):129-33. doi: 10.5214/ans.0972.7531.210403. Ann Neurosci. 2014. PMID: 25452672 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical