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. 2024 Oct 30;36(5):474-488.
doi: 10.21147/j.issn.1000-9604.2024.05.02.

Epidemiology of biliary tract cancer in China: A narrative review

Jun Zhou  1 , Guang Tan  2 , Lei Zhang  3 , Ganfeng Xie  4 , Wenting Chen  5 , Xijie Zhang  5 , Houjie Liang  4
Affiliations

Epidemiology of biliary tract cancer in China: A narrative review

Jun Zhou et al. Chin J Cancer Res. .

Abstract

Biliary tract cancer (BTC) is a group of rare malignancies that affect the gallbladder and bile ducts. Although rare, BTC is becoming a significant public health burden in China, particularly among males and older individuals. The increasing trends in BTC incidence and mortality in China are influenced by various demographic, environmental, and lifestyle factors. In this review, we examine available epidemiological data on the incidence, mortality, prognosis, and trends of different BTC subtypes in China. We also discuss the challenges and opportunities for improving the prevention, diagnosis, and management of BTC in China, and identify areas for further research and intervention. The article aims to provide a better understanding of the epidemiological features of BTC in China and to inform public health strategies and clinical practice.

Keywords: Biliary tract cancer; China; epidemiologic methods; review.

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Conflict of interest statement

Conflicts of Interest: Wenting Chen and Xijie Zhang are employees of MSD China. The other authors have no conflicts of interest to declare.Conflicts of Interest: Wenting Chen and Xijie Zhang are employees of MSD China. The other authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Summary of BTC in China. BTC, biliary tract cancer; ASIRW, age-standardized incidence rate by Segi’s population; ASMRW, age-standardized mortality rate by Segi’s population; GBC, gallbladder cancer; ECC, extrahepatic cholangiocarcinoma; ICC, intrahepatic cholangiocarcinoma.
Figure S1
Figure S1
Literature search schematic. BTC, biliary tract cancer.
See this image and copyright information in PMC

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