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Review
. 2024 Oct 30:15:1429373.
doi: 10.3389/fpsyt.2024.1429373. eCollection 2024.

A narrative exploration of psilocybin's potential in mental health

Huitae Min #  1 , Soon Young Park #  2 , Jisu Park  1   3 , Seongsu Na  1   3 , Hoe-Suk Lee  3 , Taejung Kim  1   4 , Jungyeob Ham  1   2   4 , Young-Tae Park  1   4
Affiliations
Review

A narrative exploration of psilocybin's potential in mental health

Huitae Min et al. Front Psychiatry. .

Abstract

Psilocybin, a psychoactive substance, has recently garnered attention for its high therapeutic potential in psychiatry. In this study, we investigated the multifaceted aspects of psilocybin, highlighting its chemical properties, mechanisms of action, and burgeoning role in psychiatric treatment. Furthermore, we examined the clinical applications and potential therapeutic benefits of psilocybin in the treatment of various mental health disorders, supported by accumulating clinical evidence. This review aims to deepen our understanding of the clinical impact of psilocybin, elucidate its therapeutic value, and propose directions for future research, thereby paving the way for its integration into mainstream psychiatric treatments. Psilocybin has been shown to be safe in clinical trials with manageable side effects. However, additional safety measures are required after this discussion, including dosing protocols, patient monitoring, and distress management strategies.

Keywords: dosing; mental health disorders; psilocybin; psychiatry; psychoactive.

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Conflict of interest statement

Authors SP and JH were employed by the company NeoCannBio Co., Ltd. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
The pathway of biosynthesis of psilocybin.
See this image and copyright information in PMC

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