Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Nov;26(11):1098612X241277024.
doi: 10.1177/1098612X241277024.

Evaluation of cats treated with robenacoxib after gastrointestinal surgery

Joseph B Rogers  1 , Allison S Mazepa  1 , Kathryn L Kaufman  1 , Bishoy S Eskander  1 , Andrew H Jackson  1
Affiliations

Evaluation of cats treated with robenacoxib after gastrointestinal surgery

Joseph B Rogers et al. J Feline Med Surg. 2024 Nov.

Abstract

Objectives: The aim of the study was to determine if cats administered robenacoxib immediately after gastrointestinal surgery have a similar complication rate to cats that were not administered robenacoxib.

Methods: Medical records were reviewed for 154 cats that underwent gastrointestinal surgery between December 2015 and September 2021 in this retrospective study. Data collected included patient signalment, presenting complaint, surgical procedure(s) performed, robenacoxib administration and major postoperative complications. Cats were excluded if they did not have a 2-week postoperative follow-up examination. Two groups were analyzed: group R (postoperative robenacoxib administration) consisted of 43 cats; and group C (no postoperative robenacoxib administration) consisted of 111 cats.

Results: Complications occurred in 10/43 (23.2%) cats in group R and 34/111 (30.6%) cats in group C. Major complications occurred in 1/43 (2.3%) in group R and 14/111 (12.6%) in group C. Minor complications occurred in 9/43 (20.9%) cats in group R and 20/111 (18.0%) cats in group C. One of 43 cats (2.3%) in group R and 10/111 (9.0%) cats in group C were euthanized or died within 0-16 days after gastrointestinal surgery.

Conclusions and relevance: Cats that were administered robenacoxib postoperatively did not have an increase in major postoperative complications after gastrointestinal surgery compared with cats that were administered an alternative analgesic medication. The use of robenacoxib in cats after gastrointestinal surgery may be a safe analgesic option for postoperative pain control.

Keywords: Gastrointestinal surgery; NSAIDs; non-steroidal anti-inflammatory drugs; postoperative; robenacoxib.

PubMed Disclaimer

Conflict of interest statement

Conflict of interestAHJ was a previous key opinion leader for Novartis and Onsior, before Onsior was sold to Elanco.

References

    1. Steagall PV, Robertson S, Simon B, et al.. 2022 ISFM consensus guidelines on the management of acute pain in cats. J Feline Med Surg 2022; 24: 4–30. - PMC - PubMed
    1. King S, Roberts ES, Roycroft LM, et al.. Evaluation of oral robenacoxib for the treatment of postoperative pain and inflammation in cats: results of a randomized clinical trial. ISRN Vet Sci 2012; 2012. DOI: 10.5402/2012/794148. - PMC - PubMed
    1. Bauquier SH. Randomized clinical trial comparing the perioperative analgesic efficacy of oral tramadol and intramuscular tramadol in cats. J Feline Med Surg 2022; 24: 683–690. - PMC - PubMed
    1. King S, Roberts ES, King JN. Evaluation of injectable robenacoxib for the treatment of post-operative pain in cats: results of a randomized, masked, placebo-controlled clinical trial. BMC Vet Res 2016; 12: 215. DOI: 10.1186/s12917-016-0827-0. - PMC - PubMed
    1. Rushfeldt CF, Sveinbjørnsson B, Søreide K, et al.. Risk of anastomotic leakage with use of NSAIDs after gastrointestinal surgery. Int J Colorectal Dis 2011; 26: 1501–1509. - PubMed

MeSH terms

LinkOut - more resources