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. 2024 Nov 14;73(45):1036-1042.
doi: 10.15585/mmwr.mm7345a4.

Progress Toward Measles Elimination - Worldwide, 2000-2023

Progress Toward Measles Elimination - Worldwide, 2000-2023

Anna A Minta et al. MMWR Morb Mortal Wkly Rep. .

Abstract

Measles vaccination effectively prevents measles, a highly contagious disease that can cause severe complications and death and requires high population immunity to interrupt transmission. This report describes measles elimination progress during 2000-2023. During 2000-2023, an estimated 60.3 million measles deaths were averted by vaccination. However, despite commitment from all six World Health Organization regions to eliminate measles, no region has successfully achieved and maintained measles elimination as of the end of 2023. During the COVID-19 pandemic, estimated global coverage with the first dose of measles-containing vaccine (MCV1) declined to 81%, the lowest level since 2008. MCV1 coverage improved to 83% in 2022 but was unchanged in 2023. From 2022 to 2023, estimated measles cases increased 20% worldwide, from 8,645,000 to 10,341,000; the number of countries experiencing large or disruptive outbreaks increased from 36 to 57. Estimated measles deaths decreased 8%, from 116,800 in 2022 to 107,500 in 2023, primarily because an increased number of cases occurred in countries with lower risk for death. The stagnation in MCV1 coverage means millions of children remain unprotected, leading to increases in cases and outbreaks. Coverage with measles-containing vaccine (MCV) is lower, and measles incidence is higher, in low-income countries and countries experiencing fragile, conflict-affected, and vulnerable settings, which exacerbate inequities. Urgent and targeted efforts are needed to ensure that all children receive 2 MCV doses and that surveillance is strengthened to hasten progress toward measles elimination.

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Conflict of interest statement

All authors have completed and submitted the International Committee of Medical Journal Editors form for disclosure of potential conflicts of interest. Matt Ferrari reports institutional support from the World Health Organization, Gavi, the Vaccine Alliance, and the Bill and Melinda Gates Foundation; grants or contracts from Gavi, the Vaccine Alliance, the Bill and Melinda Gates Foundation, and the National Science Foundation; and travel support from the World Health Organization, the Bill and Melinda Gates Foundation, and Imperial College. No other potential conflicts of interest were disclosed.

Figures

FIGURE
FIGURE
Estimated number of annual measles deaths with measles vaccination and in the absence of measles vaccination — worldwide, 2000–2023, * With 95% CIs indicated by error bars. Deaths prevented by vaccination are estimated by the area between estimated deaths with vaccination and those without vaccination. A cumulative total of 60.3 million deaths were estimated to have been prevented by measles vaccination during 2000–2023.

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