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Review
. 2025 Jan;43(1):95-102.
doi: 10.1016/j.det.2024.08.007. Epub 2024 Sep 10.

Innovation in Warts and Molluscum: An Updated Comprehensive Review

Kritin K Verma  1 , Kevin M Burningham  2 , Stephen K Tyring  3
Affiliations
Review

Innovation in Warts and Molluscum: An Updated Comprehensive Review

Kritin K Verma et al. Dermatol Clin. 2025 Jan.

Abstract

This comprehensive review article gives an up-to-date assessment of the therapeutic landscape for warts and molluscum contagiosum (MC), focusing on advances made in the last 5 years. New treatment choices include VP-102 (Ycanth) for molluscum contagiosum, potentially intralesional Vitamin D3 for warts, and topical cidofovir for both. Immunotherapy is regarded as a potential option, especially in difficult situations. Traditional therapies like cryotherapy and keratolytic medicines remain the principal options. The study emphasizes the need for personalized treatment strategies and additional research to improve therapy efficacy and safety.

Keywords: Cidofovir; Cryotherapy; Immunotherapy; Intralesional vitamin D3; Keratolytic agents; Molluscum contagiosum; VP-102 (ycanth); Warts.

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Conflict of interest statement

Disclosure The authors declare no disclosures.. Authors’ contributions: K.K. Verma and K.M. Burningham wrote and revised the article and performed a literature review. S.K. Tyring revised the article. All authors approved the final article.