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. 2025 Apr;46(4):1941-1944.
doi: 10.1007/s10072-024-07877-y. Epub 2024 Nov 15.

Clinical relapse after 52 years in myelin oligodendrocyte glycoprotein antibody-associated disease

Benjamin P Trewin  1   2 , Hanka Laue-Gizzi  3 , John Downie  4 , Ian Francis  4 , Sudarshini Ramanathan  1   2   5 , Todd A Hardy  6   7
Affiliations

Clinical relapse after 52 years in myelin oligodendrocyte glycoprotein antibody-associated disease

Benjamin P Trewin et al. Neurol Sci. 2025 Apr.
No abstract available

Keywords: Demyelination; MOGAD; Magnetic resonance imaging; Multiple sclerosis; Myelin oligodendrocyte glycoprotein; NMOSD; Neuromyelitis optica spectrum disorder; OCT.

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Conflict of interest statement

Declarations. Informed consent: Complete written informed consent was obtained from the patient for the publication of this case and accompanying images. Competing interests: The author(s) declared no potential competing interests with respect to the research, authorship, and/or publication of this article.

References

    1. Trewin BP, Dale RC, Qiu J et al (2024) Oral corticosteroid dosage and taper duration at onset in myelin oligodendrocyte glycoprotein antibody-associated disease influences time to first relapse. J Neurol. https://doi.org/10.1136/jnnp-2024-333463 . Neurosurg Psychiatry jnnp-2024-333463 - DOI
    1. Gigengack NK, Oertel FC, Motamedi S et al (2022) Structure–function correlates of vision loss in neuromyelitis optica spectrum disorders. Sci Rep 12:17545. https://doi.org/10.1038/s41598-022-19848-4 - DOI - PubMed - PMC
    1. Banwell B, Bennett JL, Marignier R et al (2023) Diagnosis of myelin oligodendrocyte glycoprotein antibody-associated disease: International MOGAD Panel proposed criteria. Lancet Neurol 22:268–282. https://doi.org/10.1016/s1474-4422(22)00431-8 - DOI - PubMed
    1. Deschamps R, Pique J, Ayrignac X et al (2021) The long-term outcome of MOGAD: an observational national cohort study of 61 patients. Eur J Neurol 28:1659–1664. https://doi.org/10.1111/ene.14746 - DOI - PubMed
    1. Mayuzumi Y, Kitazawa Y, Kunimatsu T (2023) Relapse of myelin oligodendrocyte glycoprotein antibody-associated demyelinating disease in an elderly patient after long-term remission. Acta Neurol Belg 123:1531–1532. https://doi.org/10.1007/s13760-022-01983-4 - DOI - PubMed

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