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. 1986 Jan 1;233(1):37-40.
doi: 10.1042/bj2330037.

A bovine epithelial membrane protein that binds polymeric immunoglobulin and has a structure related to that of bovine secretory component

D Beale, J Hopley

A bovine epithelial membrane protein that binds polymeric immunoglobulin and has a structure related to that of bovine secretory component

D Beale et al. Biochem J. .

Abstract

A protein of Mr 94000 was isolated from detergent-solubilized bovine intestinal, liver and mammary-gland membranes. It binds immunoglobulin M and also undergoes proteolytic fragmentation in a similar manner to bovine secretory component (Mr 74000). The affinity-purified membrane protein is therefore most likely to be the bovine epithelial receptor for polymeric immunoglobulin. A structural model is proposed.

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