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Review
. 2024 Dec:102:102582.
doi: 10.1016/j.arr.2024.102582. Epub 2024 Nov 14.

Semaglutide as a possible therapy for healthy aging: Targeting the hallmarks of aging

Gabriela Ueta Ortiz  1 , Ellen Cristini de Freitas  2
Affiliations
Review

Semaglutide as a possible therapy for healthy aging: Targeting the hallmarks of aging

Gabriela Ueta Ortiz et al. Ageing Res Rev. 2024 Dec.

Abstract

With an aging population, the investigation of therapies that promote healthy aging becomes increasingly urgent. Here we discuss how Semaglutide can be a potential therapy to contribute to this goal by targeting key hallmarks of aging, such as inflammation, oxidative stress and stem cell exhaustion.

Keywords: Healthy aging; Inflammation; Oxidative stress; Semaglutide; Stem cell exhaustion.

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Conflict of interest statement

Declaration of Competing Interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Ellen Cristini de Freitas reports financial support was provided by State of Sao Paulo Research Foundation. Gabriela Ueta Ortiz reports financial support was provided by State of Sao Paulo Research Foundation. Ellen Cristini de Freitas reports financial support was provided by National Council for Scientific and Technological Development. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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