Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2025 Feb;43(1):1-13.
doi: 10.1016/j.ncl.2024.07.001. Epub 2024 Sep 17.

ICU Delirium

Affiliations
Review

ICU Delirium

Amra Sakusic et al. Neurol Clin. 2025 Feb.

Abstract

Delirium is not a harmless transient event during ICU hospitalization; rather, it is a severe complication of critical illness associated with increased mortality, morbidity, and persistent disability. Despite being recognized for decades, it remains underdiagnosed. Employing validated tools for detection helps reduce missed cases. Early detection facilitates prompt management. Sedatives, opioids, and antipsychotics should be avoided whenever possible. Optimizing environmental triggers, minimizing iatrogenicity, and treating underlying critical illness constitute the basis of the currently recommended approach to diminish the burden of delirium in ICU patients.

Keywords: Critical illness; ICU delirium; Iatrogenicity; Predisposing and precipitating risk factors.

PubMed Disclaimer

Conflict of interest statement

Disclosure Authors declare that they have no conflict of interest.