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Review
. 2025 Mar-Apr;101 Suppl 1(Suppl 1):S10-S17.
doi: 10.1016/j.jped.2024.10.004. Epub 2024 Nov 14.

Microplastics: the hidden danger

Marilyn Urrutia-Pereira  1 , Paulo Augusto Camargos  2 , Dirceu Solé  3
Affiliations
Review

Microplastics: the hidden danger

Marilyn Urrutia-Pereira et al. J Pediatr (Rio J). 2025 Mar-Apr.

Abstract

Objective: To assess the impact of microplastics/nanoplastics (MiP/NP) on human health.

Data source: The authors conducted a narrative review of articles published in English, Portuguese, French and Spanish in the last decade in the following databases: PubMed, Google Scholar, EMBASE and SciELO. The keywords used in this search were: microplastics OR nanoplastics OR marine litter OR toxicology OR additives AND human health OR children OR adults.

Data synthesis: MiP is a group of emerging contaminants that have attracted increasing scientific interest and attention from society in the last decade due to their ubiquitous detection in all environments. Humans can be mainly exposed to MiP and NP orally, by inhalation, by dermal contact, as well as through systemic routes and cannot be neglected, especially in young children. The possible toxic effects in different systems are due to plastic particles, often combined with leachable additives and adsorbed contaminants.

Conclusions: Unless the plastics value chain is transformed in the next two decades, the risks to species, marine ecosystems, climate, health, economies and communities will become unmanageable. However, alongside these risks lie unique opportunities to lead the transition to a more sustainable world.

Keywords: Human health; Marine litter; Microplastics; Nanoplastics; Toxicology.

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Conflict of interest statement

Conflicts of interest The authors declare no conflicts of interest.

References

    1. Landrigan P.J., Raps H., Cropper M., Bald C., Brunner M., Canonizado E.M., et al. The Minderoo-Monaco Commission on plastics and human health. Ann Glob Health. 2023;89:23. - PMC - PubMed
    1. Ainali M.N., Kalaronis D., Kontogiannis A., Evgenidou E., Kyzas G.Z., Yang X., et al. Microplastics in the environment: sampling, pretreatment, analysis and occurrence based on current and newly-exploited chromatographic approaches. Sci Total Environ. 2021;794 - PubMed
    1. Street M.E., Bernasconi S. Microplastics, environment and child health. Ita J Pediatr. 2021;47:75. - PMC - PubMed
    1. Bai C.L., Wang D., Luan Y.L., Huang S.N., Liu L.Y., Guo Y. A review on micro- and nanoplastics in humans: implication for their translocation of barriers and potential health effects. Chemosphere. 2024;361 - PubMed
    1. Toussaint B., Raffael B., Angers-Loustau A., Gilliland D., Kestens V., Petrillo M., et al. Review of micro- and nanoplastic contamination in the food chain. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2019;36:639–673. - PubMed