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. 1986 Feb;49(2):501-7.
doi: 10.1016/S0006-3495(86)83660-8.

Thermodynamics of cell adhesion. II. Freely mobile repellers

D C Torney, M Dembo, G I Bell

Thermodynamics of cell adhesion. II. Freely mobile repellers

D C Torney et al. Biophys J. 1986 Feb.

Abstract

The equilibrium adhesion of a cell or vesicle to a substrate is analyzed in a theoretical model in which two types of mobile molecules in the cell membrane are of interest: receptors that can form bonds with fixed ligands in the substrate and repellers that repel the substrate. If the repulsion between the repeller molecule and substrate is greater than kT, there is substantial redistribution of the repellers from the contact area. Coexisting equilibrium states are observed having comparable free energies (a) with unstretched bonds and repeller redistribution and (b) with stretched bonds and partial redistribution.

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References

    1. J Biol Chem. 1979 Nov 10;254(21):10830-8 - PubMed
    1. Biol Rev Camb Philos Soc. 1981 May;56(2):199-242 - PubMed
    1. Proc Natl Acad Sci U S A. 1981 Aug;78(8):4975-9 - PubMed
    1. Biophys J. 1985 Jul;48(1):175-83 - PubMed
    1. J Biol Chem. 1982 Dec 10;257(23):14293-9 - PubMed

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