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. 2024 Nov 15;11(6):723-732.
doi: 10.1093/nop/npae047. eCollection 2024 Dec.

Health-related quality of life in surgically treated asymptomatic meningioma patients: A population-based matched cohort study

Olivia Näslund  1   2 , Stina Jakobsson  3   4 , Erik Thurin  1   5 , Thomas Skoglund  1   6 , Jenny Pettersson-Segerlind  7   8 , Boel Brynedal  9 , Asgeir S Jakola  1   6 , Jiri Bartek Jr  7   8   10
Affiliations

Health-related quality of life in surgically treated asymptomatic meningioma patients: A population-based matched cohort study

Olivia Näslund et al. Neurooncol Pract. .

Abstract

Background: Asymptomatic patients with meningiomas are increasingly detected, where management can be challenging in terms of surgery versus watchful waiting. Health-related quality of life (HRQoL) is an important factor in clinical decision-making, albeit not greatly studied in this patient group. The aim of this paper is to map the HRQoL among patients with surgically removed asymptomatic meningioma as compared to the general population.

Methods: Patients with first-time surgically treated asymptomatic meningioma between 2007 and 2013 were identified. Patients were invited in 2017 to answer a survey regarding different aspects of quality of life, using EuroQoL (EQ)-5D-3L, perceived health, lifestyle, and occupancy. Data from electronic patient records was obtained. The patients were matched based on age and gender with data from the Stockholm Region Public Health Cohort database.

Results: There was no difference in EQ-5D-3L or visual analog scale between the patients and their matched controls. Patients and controls experienced ill health to the same extent, but patients felt to a greater extent that this impacted their way of life. In 36% of patients, preoperative occupation was not resumed, mostly due to cognitive symptoms. Additionally, the study suggested social detachment in this cohort, as significantly more patients were living alone and had less emotional support compared to controls.

Conclusions: Although surgically treated patients with asymptomatic intracranial meningioma have similar overall HRQoL compared to the general population, surgery has an impact on return to work and cognitive function.

Keywords: asymptomatic; health-related quality of life; incidental; meningioma; population-based.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Figure 1.
Figure 1.
Flowchart of search strategy.
Figure 2.
Figure 2.
EQ-5D-3L visual analogue scale and TTO value comparison of patient versus control between all individuals, females, and males.
See this image and copyright information in PMC

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