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Published Erratum
. 2025 Jan;12(1):e200348.
doi: 10.1212/NXI.0000000000200348. Epub 2024 Nov 18.

Pediatric MOG-Ab-Associated Encephalitis: Supporting Early Recognition and Treatment

No authors listed
Published Erratum

Pediatric MOG-Ab-Associated Encephalitis: Supporting Early Recognition and Treatment

No authors listed. Neurol Neuroimmunol Neuroinflamm. 2025 Jan.
No abstract available

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Figures

Figure 5
Figure 5. Evolution of MRI Lesion Patterns During an Acute Attack and Subsequent Attacks in 2 Different Patients
(A–E) Case 1. Axial T2 weighted image performed during 1st acute attack shows patchy hyperintense lesions involving the deep gray nuclei (arrows, A), which resolved on the follow up MRI 3 months later (B) Second attack, 4 years later, T2 weighted sequence at this point showed diffuse cerebral edema evidenced by sulcal and ventricular effacement in addition to new thalamic and basal ganglia lesions (arrows, C)- these changes resolved on 3 months follow up MRI (D). MRI during third attack (8 years from initial attack) showed bilateral cortical lesions in addition to the deep gray lesions (arrows, E). (F–I) Case 2. MRI at symptom onset (headache, lethargy, and ataxia) was normal, except for features of raised intracranial pressure, evidenced by bilateral posterior scleral flattening (arrows, F). Note normal appearance of the brainstem and cerebellum (G). CSF opening pressure was found to be 40 cm, and patient was treated as ‘idiopathic intracranial hypertension’. A repeat MRI was performed 3 weeks later due to ongoing clinical symptomatology, which shows patchy T2/FLAIR hyperintense lesions involving the brainstem, middle cerebellar peduncles, and cerebellar white matter (arrows, H) as well as the left hypothalamus and right thalamus (arrows, I).
See this image and copyright information in PMC

Erratum for

  • Pediatric MOG-Ab-Associated Encephalitis: Supporting Early Recognition and Treatment.
    Kim NN, Champsas D, Eyre M, Abdel-Mannan O, Lee V, Skippen A, Chitre MV, Forsyth R, Hemingway C, Kneen R, Lim M, Ram D, Ramdas S, Wassmer E, West S, Wright S, Biswas A, Mankad K, Flanagan EP, Palace J, Rossor T, Ciccarelli O, Hacohen Y. Kim NN, et al. Neurol Neuroimmunol Neuroinflamm. 2024 Dec;11(6):e200323. doi: 10.1212/NXI.0000000000200323. Epub 2024 Oct 11. Neurol Neuroimmunol Neuroinflamm. 2024. PMID: 39393046 Free PMC article.

References

    1. Kim NN, Champsas D, Eyre M, et al. . Pediatric MOG-Ab–associated encephalitis: supporting early recognition and treatment. Neurol Neuroimmunol Neuroinflamm. 2024;11(6):e200323. doi:10.1212/NXI.0000000000200323 - DOI - PMC - PubMed

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