Cutaneous leishmaniasis: a neglected clinical manifestation among the tribal population in Nilambur, Kerala, India
- PMID: 39558844
- DOI: 10.1093/trstmh/trae102
Cutaneous leishmaniasis: a neglected clinical manifestation among the tribal population in Nilambur, Kerala, India
Abstract
Background: Different clinical manifestations of leishmaniasis (cutaneous and visceral) caused by Leishmania donovani have been reported from Kerala, India. Leishmania donovani causing cutaneous leishmaniasis (CL) (also called atypical CL [ACL]) is one of the major health concerns in the Western Ghats belt of the state.
Methods: Skin biopsies of 20 patients with suspected CL from Nilambur, Kerala, were processed for CL diagnosis during the period 2022-2023. Parasite species were characterized using Leishmania-specific Internal Transcribed Spacer-Ⅰ (ITS-Ⅰ) PCR and ITS-Ⅰ RFLP analysis.
Result: A total of 18 cases were confirmed to be CL and the parasite was identified as L. donovani.
Conclusion: These indigenous ACL (CL due to L. donovani) reports from the small foci of Nilambur reveal an emerging endemic zone of leishmaniasis in the Western Ghats.
Keywords: Leishmania donovani; Kerala; Western Ghats; atypical cutaneous leishmaniasis.
© The Author(s) 2024. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene.
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