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. 2025 Apr 1;119(4):393-395.
doi: 10.1093/trstmh/trae102.

Cutaneous leishmaniasis: a neglected clinical manifestation among the tribal population in Nilambur, Kerala, India

Affiliations

Cutaneous leishmaniasis: a neglected clinical manifestation among the tribal population in Nilambur, Kerala, India

P A Fathima et al. Trans R Soc Trop Med Hyg. .

Abstract

Background: Different clinical manifestations of leishmaniasis (cutaneous and visceral) caused by Leishmania donovani have been reported from Kerala, India. Leishmania donovani causing cutaneous leishmaniasis (CL) (also called atypical CL [ACL]) is one of the major health concerns in the Western Ghats belt of the state.

Methods: Skin biopsies of 20 patients with suspected CL from Nilambur, Kerala, were processed for CL diagnosis during the period 2022-2023. Parasite species were characterized using Leishmania-specific Internal Transcribed Spacer-Ⅰ (ITS-Ⅰ) PCR and ITS-Ⅰ RFLP analysis.

Result: A total of 18 cases were confirmed to be CL and the parasite was identified as L. donovani.

Conclusion: These indigenous ACL (CL due to L. donovani) reports from the small foci of Nilambur reveal an emerging endemic zone of leishmaniasis in the Western Ghats.

Keywords: Leishmania donovani; Kerala; Western Ghats; atypical cutaneous leishmaniasis.

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