Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2024 Nov 15;103(46):e40419.
doi: 10.1097/MD.0000000000040419.

The diagnostic value of endoscopic ultrasound for esophageal subepithelial lesions: A review

Wanwen Li  1 , Mengqi Shao  2 , Shichen Hu  1 , Shenglong Xie  1 , Bin He  1
Affiliations
Review

The diagnostic value of endoscopic ultrasound for esophageal subepithelial lesions: A review

Wanwen Li et al. Medicine (Baltimore). .

Abstract

Esophageal subepithelial lesions (ESELs) encompass a variety of diseases, including leiomyoma, granular cell tumors, hemangioma, lipoma, stromal tumors, leiomyosarcoma, schwannoma, neuroendocrine tumors and more. These lesions often present asymptomatically, leading to a generally low clinical diagnosis rate. Common imaging techniques for diagnosing ESELs include conventional endoscopy, spiral computed tomography, and endoscopic ultrasound (EUS). Among these, EUS is currently regarded as one of the most accurate methods for diagnosing ESELs. In recent years, EUS has increasingly been combined with advanced technologies such as artificial intelligence, submucosal saline injection, high-frequency impedance measurement, and enhanced imaging to improve diagnostic accuracy and reduce missed diagnoses. This article reviews the application and recent advancements of EUS in diagnosing esophageal submucosal lesions.

PubMed Disclaimer

Conflict of interest statement

The authors have no conflicts of interest to disclose.

Figures

Figure 1.
Figure 1.
The origin and the characteristic appearance of 4 common esophageal subepithelial lesions (including leiomyoma, granular cell tumor, lipoma, and hemangioma) on EUS. EUS = endoscopic ultrasound.
Figure 2.
Figure 2.
Characterization and application of common esophageal subepithelial tumors under EUS. EUS = endoscopic ultrasound.
See this image and copyright information in PMC

Similar articles

See all similar articles

References

    1. Sharzehi K, Sethi A, Savides T. AGA clinical practice update on management of subepithelial lesions encountered during routine endoscopy: expert review. Clin Gastroenterol Hepatol. 2022;20:2435–43.e4. - PubMed
    1. Lewis RB, Mehrotra AK, Rodriguez P, Levine MS. From the radiologic pathology archives: esophageal neoplasms: radiologic-pathologic correlation. Radiographics. 2013;33:1083–108. - PubMed
    1. Lee LS, Singhal S, Brinster CJ, et al. . Current management of esophageal leiomyoma. J Am Coll Surg. 2004;198:136–46. - PubMed
    1. Álvarez Martínez P, Ramos Martínez PJ, García González P, Nieto-Jara A, Del Caño Cerdán C, García Riesco E. Primary esophageal diffuse large B-cell lymphoma. Rev Esp Enferm Dig. 2023;115:400–1. - PubMed
    1. Peño Muñoz L, Boix Clemente C, Martí Romero L, et al. . A rare endoscopic finding: primary esophageal melanoma. Rev Esp Enferm Dig. 2023;115:396–7. - PubMed

MeSH terms