Proteomic Signature of BMI and Risk of Type 2 Diabetes

doi:10.2337/db24-0329

. 2025 Feb 1;74(2):234-242.

doi: 10.2337/db24-0329.

Proteomic Signature of BMI and Risk of Type 2 Diabetes

Xuan Wang¹, Hao Ma¹, Minghao Kou¹, Yoriko Heianza¹, Vivian Fonseca^{2

3}, Lu Qi^{1

4}

Affiliations

¹ Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA.
² Section of Endocrinology and Metabolism, Tulane University School of Medicine, New Orleans, LA.
³ Southeast Louisiana Veterans Health Care System, New Orleans, LA.
⁴ Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.

PMID: 39561322
PMCID: PMC11755684 (available on 2026-02-01)
DOI: 10.2337/db24-0329

Proteomic Signature of BMI and Risk of Type 2 Diabetes

Xuan Wang et al. Diabetes. 2025.

. 2025 Feb 1;74(2):234-242.

doi: 10.2337/db24-0329.

Authors

Xuan Wang¹, Hao Ma¹, Minghao Kou¹, Yoriko Heianza¹, Vivian Fonseca^{2

3}, Lu Qi^{1

4}

Affiliations

¹ Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA.
² Section of Endocrinology and Metabolism, Tulane University School of Medicine, New Orleans, LA.
³ Southeast Louisiana Veterans Health Care System, New Orleans, LA.
⁴ Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.

PMID: 39561322
PMCID: PMC11755684 (available on 2026-02-01)
DOI: 10.2337/db24-0329

No abstract available

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Conflict of interest statement

Duality of Interest. No potential conflicts of interest relevant to this article were reported.

References

1. American Diabetes Association Professional Practice Committee. 8. Obesity and weight management for the prevention and treatment of type 2 diabetes: Standards of Medical Care in Diabetes—2022. Diabetes Care 2022;45(Suppl. 1):S113–S124 - PubMed
1. US Preventive Services Task Force; Davidson KW, Barry MJ, Mangione CM, et al. . Screening for prediabetes and type 2 diabetes: US Preventive Services Task Force recommendation statement. JAMA 2021;326:736–743 - PubMed
1. Neeland IJ, Poirier P, Després J-P.. Cardiovascular and metabolic heterogeneity of obesity: clinical challenges and implications for management. Circulation 2018;137:1391–1406 - PMC - PubMed
1. Elmaleh-Sachs A, Schwartz JL, Bramante CT, Nicklas JM, Gudzune KA, Jay M.. Obesity management in adults: a review. JAMA 2023;330:2000–2015 - PMC - PubMed
1. Tomiyama AJ, Hunger JM, Nguyen-Cuu J, Wells C.. Misclassification of cardiometabolic health when using body mass index categories in NHANES 2005–2012. Int J Obes (Lond) 2016;40:883–886 - PubMed

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[1] American Diabetes Association Professional Practice Committee. 8. Obesity and weight management for the prevention and treatment of type 2 diabetes: Standards of Medical Care in Diabetes—2022. Diabetes Care 2022;45(Suppl. 1):S113–S124 - PubMed

[2] American Diabetes Association Professional Practice Committee. 8. Obesity and weight management for the prevention and treatment of type 2 diabetes: Standards of Medical Care in Diabetes—2022. Diabetes Care 2022;45(Suppl. 1):S113–S124 - PubMed

[3] US Preventive Services Task Force; Davidson KW, Barry MJ, Mangione CM, et al. . Screening for prediabetes and type 2 diabetes: US Preventive Services Task Force recommendation statement. JAMA 2021;326:736–743 - PubMed

[4] US Preventive Services Task Force; Davidson KW, Barry MJ, Mangione CM, et al. . Screening for prediabetes and type 2 diabetes: US Preventive Services Task Force recommendation statement. JAMA 2021;326:736–743 - PubMed

[5] Neeland IJ, Poirier P, Després J-P.. Cardiovascular and metabolic heterogeneity of obesity: clinical challenges and implications for management. Circulation 2018;137:1391–1406 - PMC - PubMed

[6] Neeland IJ, Poirier P, Després J-P.. Cardiovascular and metabolic heterogeneity of obesity: clinical challenges and implications for management. Circulation 2018;137:1391–1406 - PMC - PubMed

[7] Elmaleh-Sachs A, Schwartz JL, Bramante CT, Nicklas JM, Gudzune KA, Jay M.. Obesity management in adults: a review. JAMA 2023;330:2000–2015 - PMC - PubMed

[8] Elmaleh-Sachs A, Schwartz JL, Bramante CT, Nicklas JM, Gudzune KA, Jay M.. Obesity management in adults: a review. JAMA 2023;330:2000–2015 - PMC - PubMed

[9] Tomiyama AJ, Hunger JM, Nguyen-Cuu J, Wells C.. Misclassification of cardiometabolic health when using body mass index categories in NHANES 2005–2012. Int J Obes (Lond) 2016;40:883–886 - PubMed

[10] Tomiyama AJ, Hunger JM, Nguyen-Cuu J, Wells C.. Misclassification of cardiometabolic health when using body mass index categories in NHANES 2005–2012. Int J Obes (Lond) 2016;40:883–886 - PubMed

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Proteomic Signature of BMI and Risk of Type 2 Diabetes

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Proteomic Signature of BMI and Risk of Type 2 Diabetes

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