[Value of plasma ribonuclease as a marker for gynecologic tumors and breast tumors]

Abstract

In 151 patients the plasma-ribonuclease-activity was measured. The results of a control group of 47 patients were compared to the pretherapeutic values of 21 cases with cervical intraepithelial neoplasia, 83 cases with gynecologic cancer and 47 cases with breast cancer. The upper limit of the normal range was 300 ng/ml. The method is not appropriate for the detection of precancer of the uterine cervix or for breast cancer. For gynecologic tumors we found a sensitivity rate of 87% and a specificity rate of 85%.