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. 2025 Feb;14(2):e202400356.
doi: 10.1002/open.202400356. Epub 2024 Nov 21.

Synthesis and Structural Characterization of SiO2 Nanoparticles Using Extract of Gracilaria Crassa Via Green Chemistry Approach

Vanathi Palanimuthu  1 , Rajiv Periakaruppan  2 , Valentin Romanovski  3 , Ayyarappan Bharathi  4 , Karungan Selvaraj Vijai Selvaraj  5 , Somasundaram Anukeerthana  1 , Rajendran Nishanthi  1 , Gurumoorthy Vanajadevi  1
Affiliations

Synthesis and Structural Characterization of SiO2 Nanoparticles Using Extract of Gracilaria Crassa Via Green Chemistry Approach

Vanathi Palanimuthu et al. ChemistryOpen. 2025 Feb.

Abstract

Biologically synthesized nanoparticles via biological entities are produced with less negative impact on the environment and without expensive chemicals, which have biocompatibility and are eco-friendly. Gracilaria crassa is a well-known marine red alga that is edible and unique and is the commercial source of agar and agarose production. In this work, Gracilaria crassa-mediated SiO2 NPs were synthesized by the green synthesis method. In order to characterize the physicochemical properties of the synthesized SiO2 NPs, a variety of microscopic and spectroscopic approaches were used, including imaging with Field emission scanning electron microscopy, Energy-dispersive X-ray analysis, UV spectrophotometry, X-ray diffraction analysis, Fourier-transform infrared spectroscopy, Zeta potential, and Thermo gravimetric analysis. These results shown that Gracilaria crassa-mediated SiO2 NPs were amorphous nature, negatively charged -15.5 mV and spherical shape in size of 20-50 nm. The antioxidant capacity of synthesised SiO2 NPs was examined by 2,2-Diphenyl-1-picrylhydrazyl assay and it observed as IC50 value of 49.4 μg/mL denotes that could counteract the production of free radicals and oxidative stress. The characteristics of the synthesized Gracilara crassa-mediated SiO2 NPs suggest their application as potential antioxidant agents.

Keywords: Antioxidant; Characterization; Gracilara crassa; SiO2 nanoparticles.

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Conflict of interest statement

The authors declare no competing interest with any previous work.

Figures

Figure 1
Figure 1
UV‐vis spectra (a), XRD diffractogram (b), FTIR spectra (c), and TGA (d) analysis of synthesized SiO2 NPs.
Figure 2
Figure 2
SEM‐EDS (a), and TEM images (b) of synthesized SiO2 NPs.
Figure 3
Figure 3
Zeta potential analysis of SiO2 NPs.
Figure 4
Figure 4
Antioxidant analysis of SiO2 NPs.
See this image and copyright information in PMC

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