Prophase pairing in a mosaic 18p-;iso 18q human female foetus studied by surface spreading
- PMID: 3957350
- DOI: 10.1007/BF00291890
Prophase pairing in a mosaic 18p-;iso 18q human female foetus studied by surface spreading
Abstract
The pachytene configurations formed in the ovary of a mosaic 18p-;iso 18q human foetus (22 weeks gestation) are analysed using a surface spreading technique. Three features of interest are the apparent meiotic delay of oocyte development, oocyte degeneration, and the triple pairing which occurs in one cell line when the iso 18q both pairs with itself and with the normal chromosome 18.
Similar articles
-
Meiosis in the foetal mouse ovary. I. An analysis at the light microscope level using surface-spreading.Chromosoma. 1982;85(3):427-37. doi: 10.1007/BF00330366. Chromosoma. 1982. PMID: 6180868
-
Prenatal detection of monosomy 18p and trisomy 18q mosaicism with unexpected fetal phenotype.J Med Genet. 1986 Jun;23(3):258-9. doi: 10.1136/jmg.23.3.258. J Med Genet. 1986. PMID: 3723556 Free PMC article.
-
Continuous loss of oocytes throughout meiotic prophase in the normal mouse ovary.Dev Biol. 2003 Jun 15;258(2):334-48. doi: 10.1016/s0012-1606(03)00132-5. Dev Biol. 2003. PMID: 12798292
-
[Changes in the relative arrangement of the chromosomes and nucleolus in developing mammalian oocytes during meiotic prophase I in relation to functional changes in the oocytes].Tsitologiia. 1992;34(11-12):3-23. Tsitologiia. 1992. PMID: 1302392 Review. Russian.
-
On the origin of the maternal age effect in trisomy 21 Down syndrome: the Oocyte Mosaicism Selection model.Reproduction. 2010 Jan;139(1):1-9. doi: 10.1530/REP-09-0088. Reproduction. 2010. PMID: 19755486 Review.
Cited by
-
Oocyte development in XO foetuses of man and mouse: the possible role of heterologous X-chromosome pairing in germ cell survival.Chromosoma. 1986;94(2):115-24. doi: 10.1007/BF00286989. Chromosoma. 1986. PMID: 3757617
-
Prophase of meiosis in human spermatocytes analysed by EM microspreading in infertile men and their controls and comparisons with human oocytes.Hum Genet. 1990 May;84(6):547-54. doi: 10.1007/BF00210808. Hum Genet. 1990. PMID: 2338341
-
The possible role of meiotic pairing anomalies in the atresia of human fetal oocytes.Hum Genet. 1988 Mar;78(3):260-6. doi: 10.1007/BF00291673. Hum Genet. 1988. PMID: 3346015
-
Turner syndrome and female sex chromosome aberrations: deduction of the principal factors involved in the development of clinical features.Hum Genet. 1995 Jun;95(6):607-29. doi: 10.1007/BF00209476. Hum Genet. 1995. PMID: 7789944 Review.
-
Centric fission--simple and complex mechanisms.Chromosome Res. 2004;12(6):627-40. doi: 10.1023/B:CHRO.0000036594.38997.59. Chromosome Res. 2004. PMID: 15289668 Review.