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. 2024 Nov 7:11:1436470.
doi: 10.3389/fmed.2024.1436470. eCollection 2024.

Enhanced skin cancer diagnosis through grid search algorithm-optimized deep learning models for skin lesion analysis

Affiliations

Enhanced skin cancer diagnosis through grid search algorithm-optimized deep learning models for skin lesion analysis

Rudresh Pillai et al. Front Med (Lausanne). .

Abstract

Skin cancer is a widespread and perilous disease that necessitates prompt and precise detection for successful treatment. This research introduces a thorough method for identifying skin lesions by utilizing sophisticated deep learning (DL) techniques. The study utilizes three convolutional neural networks (CNNs)-CNN1, CNN2, and CNN3-each assigned to a distinct categorization job. Task 1 involves binary classification to determine whether skin lesions are present or absent. Task 2 involves distinguishing between benign and malignant lesions. Task 3 involves multiclass classification of skin lesion images to identify the precise type of skin lesion from a set of seven categories. The most optimal hyperparameters for the proposed CNN models were determined using the Grid Search Optimization technique. This approach determines optimal values for architectural and fine-tuning hyperparameters, which is essential for learning. Rigorous evaluations of loss, accuracy, and confusion matrix thoroughly assessed the performance of the CNN models. Three datasets from the International Skin Imaging Collaboration (ISIC) Archive were utilized for the classification tasks. The primary objective of this study is to create a robust CNN system that can accurately diagnose skin lesions. Three separate CNN models were developed using the labeled ISIC Archive datasets. These models were designed to accurately detect skin lesions, assess the malignancy of the lesions, and classify the different types of lesions. The results indicate that the proposed CNN models possess robust capabilities in identifying and categorizing skin lesions, aiding healthcare professionals in making prompt and precise diagnostic judgments. This strategy presents an optimistic avenue for enhancing the diagnosis of skin cancer, which could potentially decrease avoidable fatalities and extend the lifespan of people diagnosed with skin cancer. This research enhances the discipline of biomedical image processing for skin lesion identification by utilizing the capabilities of DL algorithms.

Keywords: Convolutional Neural Network (CNN); binary classification; deep learning (DL); grid search algorithm; multiclass classification; skin cancer; skin lesions.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.

Figures

Figure 1
Figure 1
Flowchart for proposed methodology of complete diagnosis of skin lesions.
Figure 2
Figure 2
Classification task 1: skin lesion detection dataset images.
Figure 3
Figure 3
Classification task 2: classification of benign and malignant dataset images.
Figure 4
Figure 4
Classification task 3: benign/malignant skin lesion classification in seven classes dataset images.
Figure 5
Figure 5
Data augmentation (A) original image, (B) rotate, (C) zoom, (D) horizontal flip, and (E) vertical flip.
Figure 6
Figure 6
Framework of proposed CNN model 1 for skin lesion detection task 1. (A) CNN model 1, and (B) Conv block.
Figure 7
Figure 7
Framework of proposed CNN model 2 for benign/malignant lesion classification task 2.
Figure 8
Figure 8
Framework of proposed CNN model 3 for classification task 3 of benign/malignant skin lesion classification in seven classes.
Figure 9
Figure 9
Results of proposed CNN model 1 for classification task 1 (A) Loss analysis plot, and (B) accuracy analysis plot.
Figure 10
Figure 10
Confusion matrix achieved for classification task 1.
Figure 11
Figure 11
Results of proposed CNN model 2 for classification task 2. (A) Loss analysis plot, and (B) accuracy analysis plot.
Figure 12
Figure 12
Confusion matrix achieved for classification task 2.
Figure 13
Figure 13
Results of proposed CNN model 3 for classification task 3. (A) Loss analysis plot, and (B) accuracy analysis plot.
Figure 14
Figure 14
Confusion matrix achieved for classification task 3.

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