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Review
. 2024 Nov 7:15:1465387.
doi: 10.3389/fphar.2024.1465387. eCollection 2024.

Inspired by an ancient Chinese Medicine prescription: the modern significance and potential of Yiyi Fuzi Baijiang San in treating diseases

Yuli Zhang #  1   2 , Lu Zhang #  3 , Ni Chai  4 , ZhiQiang Wan  5   6 , Hua Sui  2
Affiliations
Review

Inspired by an ancient Chinese Medicine prescription: the modern significance and potential of Yiyi Fuzi Baijiang San in treating diseases

Yuli Zhang et al. Front Pharmacol. .

Abstract

Classic Formulas (Jing fang) are considered the essence and authority of Traditional Chinese Medicine (TCM) due to their long history and proven efficacy. These formulas play a pivotal role in all kinds of different disease prevention and therapeutic strategies. Yiyi Fuzi Baijiang San (YYFZBJS), one of the Classic Formulas, was originally developed for the treatment of chronic intestinal abscess. With the accumulation of clinical experience and the exploration of modern pharmacological research in recent years, YYFZBJS has been extensively employed to address a broad spectrum of conditions such as colorectal cancer. Although numerous studies have explored the clinical efficacy and underlying mechanisms of YYFZBJS, no comprehensive review summarizing these findings exists to date. This study aims to systematically review and critically assess the current clinical and mechanistic research on YYFZBJS, with the objective of providing valuable insights and guidance for TCM research in the future.

Keywords: Yiyi Fuzi Baijiang San; active ingredients; clinical application; mechanism; traditional Chinese medicine.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The reviewer QJ declared a shared affiliation with the author NC to the handling editor at the time of the review.

Figures

FIGURE 1
FIGURE 1
Preparation process of YYFZBJS.
FIGURE 2
FIGURE 2
Representative metabolites included in YYFZBJS. (A): Coix seed; (B) Radix Aconiti Lateralis; (C) Patrinia villosa).
FIGURE 3
FIGURE 3
Signaling pathways affected by YYFZBJS.
FIGURE 4
FIGURE 4
Immune cells affected by YYFZBJS.
FIGURE 5
FIGURE 5
Intestinal flora affected by YYFZBJS.
See this image and copyright information in PMC

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