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Review
. 2025 Jan;70(1):74-84.
doi: 10.1007/s10620-024-08705-1. Epub 2024 Nov 22.

Alcohol-Associated Hepatitis: Short- and Long-Term Management

Sergio A De La Torre Jr  1 , Marco Morcos  2 , Sammy Saab  1   2 , Akshay Shetty  3   4
Affiliations
Review

Alcohol-Associated Hepatitis: Short- and Long-Term Management

Sergio A De La Torre Jr et al. Dig Dis Sci. 2025 Jan.

Abstract

Alcohol-associated hepatitis, considered a severe form of alcohol-associated liver disease, carries with it multiple negative health outcomes ranging not only to increased hospitalizations but also increased rates of mortality. While the inpatient management remains critical in optimizing clinical outcomes, a shift in focus to the outpatient management of alcohol-associated hepatitis is warranted as a long-term solution to this emerging health pandemic. Here, we review the clinical presentation, diagnosis, and current prognostication scoring systems for alcohol-associated hepatitis. We then offer a multimodal approach to the continued management of alcohol-associated hepatitis in the outpatient setting encompassing not only nutritional optimization, alcohol use disorder treatment, and the medical management of chronic liver disease, but also briefly review the current trend of the use of liver transplantation.

Keywords: Alcohol hepatitis; Severe alcohol hepatitis.

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Conflict of interest statement

Declarations. Conflict of interest: The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Nutritional assessment recommendations for patients presenting with alcohol-related hepatitis
Fig. 2
Fig. 2
Short-term management of patients presenting with severe alcohol-related hepatitis. Key: SAH—severe alcohol-related hepatitis, prn—as needed
Fig. 3
Fig. 3
Multimodality treatment of alcohol use disorder
See this image and copyright information in PMC

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