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. 2024 Dec 9;42(12):1990-1993.
doi: 10.1016/j.ccell.2024.10.018. Epub 2024 Nov 21.

Unraveling the tumor-initiating cells in hepatocellular carcinoma

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Unraveling the tumor-initiating cells in hepatocellular carcinoma

Yu Man Tsui et al. Cancer Cell. .

Abstract

Aggressive features of hepatocellular carcinoma (HCC) are highly related to liver tumor-initiating cells (TICs), which are heterogeneous and plastic. In this issue of Cancer Cell, Yang et al. reveal the ability of CD49f-high TICs in shaping the tumor immunosuppressive microenvironment in HCC.

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Conflict of interest statement

Declaration of interests The authors declare no completing interests.

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