Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Feb:194:123478.
doi: 10.1016/j.wneu.2024.11.061. Epub 2024 Dec 6.

Awake Minimally Invasive Surgery Transforaminal Lumbar Interbody Fusion Under Spinal Anesthesia: Screw Placement Accuracy and 1 Year Follow-Up

Affiliations
Free article

Awake Minimally Invasive Surgery Transforaminal Lumbar Interbody Fusion Under Spinal Anesthesia: Screw Placement Accuracy and 1 Year Follow-Up

Gaetano De Biase et al. World Neurosurg. 2025 Feb.
Free article

Abstract

Objective: We assessed the accuracy of pedicle screws placed during awake minimally invasive surgery (MIS) transforaminal lumbar interbody fusion (TLIF) under spinal anesthesia and analyzed outcomes at the 1-year follow-up.

Methods: We included patients who underwent awake MIS-TLIF under spinal anesthesia at an academic center from February 2020 to February 2022. The Gertzbein-Robbins classification was used for screw accuracy rating.

Results: A total of 100 pedicle screws were inserted in 24 patients, with the most common level being L4-5. Median age was 63.5 ± 16.5 (interquartile range) years, 42% male, median body mass index 28 ± 6 kg/m2, and median American Society of Anesthesiologists class was 2 ± 1. Two patients underwent a 2-level fusion, and 22 patients underwent a 1-level fusion. Median estimated blood loss was 35 ± 25 mL, median length of stay was 0 ± 1 day, with 54% of patients going home on the day of surgery, and the only intraoperative complication was 1 durotomy. Median procedure time was 112 ± 23.5 minutes, and median operating room time (including the spinal block) was 159.5 ± 32.7 minutes; 67% of the screws were placed with navigation, and 33% were robotic-assisted (Mazor X); 99% of the screws were Gertzbein Robins grade A, and 1% grade E. At the 1 year follow-up, computed tomography showed no evidence of pseudarthrosis, and all patients reported improvement in their presenting symptoms.

Conclusions: Our study shows a high accuracy (99%) of pedicle screw placement in patients undergoing awake MIS-TLIF under spinal anesthesia and significant improvement of their symptoms at 1-year follow-up.

Keywords: Awake fusion; Awake spine; Robotic fusion; Screw accuracy; Spinal fusion.

PubMed Disclaimer

References

LinkOut - more resources