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Review
. 2025 Mar;81(3):1145-1156.
doi: 10.1002/ps.8559. Epub 2024 Nov 23.

Cinnamamides: a review of research in the agrochemical field

Adrielle Firmino Da Silva  1 , Saraliny Bezerra França  1 , Lucas Fernando De Lima Costa  1 , Ricardo Alexandre Dos Santos  1 , Natália De Araújo Pinheiro  1 , Maria Ester De Sá Barreto Barros  1 , Dimas José Da Paz Lima  1
Affiliations
Review

Cinnamamides: a review of research in the agrochemical field

Adrielle Firmino Da Silva et al. Pest Manag Sci. 2025 Mar.

Abstract

The need for implementation of economically viable agrochemicals with lower toxicity and that are capable of overcoming resistance developed by insects, fungi and invasive plants has spurred the scientific community in the search for new active and selective substances and synthetic methodologies that adhere to the parameters of green chemistry. Cinnamamides, in turn, present a scaffold that has been a basis for various investigations due to their broad spectrum of biological activities. The agrochemical industry is a vast field in which these classes of compounds stand out, whether for their potential herbicidal, fungicidal, nematicidal, or insecticidal properties. Therefore, this review reports the progress of synthesis and the agrochemical potential of cinnamamides, their mechanism of action, and their structure-activity relationship (SAR), to provide insights for further research addressing the use of cinnamamides in crop protection. © 2024 Society of Chemical Industry.

Keywords: agrochemicals; cinnamic acid‐derived amides; pest control.

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References

REFERENCES

    1. FAO, The state of food and agriculture, The State Of Food And Agriculture (2017). http://www.fao.org/3/a-I7658e.pdf.
    1. Saeed F, Chaudhry UK, Raza A, Charagh S, Bakhsh A, Bohra A et al., Developing future heat‐resilient vegetable crops. Funct Integr Genomics 23:47 (2023).
    1. Xu H, Chen T, Huang L, Shen Q, Lian Z, Shi Y et al., Synthesis and fungicidal activity of Lansiumamide A and B and their derivatives. Molecules 23:1499 (2018).
    1. Jeschke P, Progress of modern agricultural chemistry and future prospects. Pest Manag Sci 72:433–455 (2016).
    1. Mitter N, Worrall EA, Robinson KE, Li P, Jain RG, Taochy C et al., Clay nanosheets for topical delivery of RNAi for sustained protection against plant viruses. Nat Plants 3:16207 (2017).

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