Genome sequencing reveals novel IKBKG structural variants associated with incontinentia pigmenti

Neta Pipko¹, Rachel Youjin Oh², Aiyana Kaplan², Andrea Shugar², Anna Szuto², Miriam Weinstein³, Grace Yoon^{2

4

5}, Roberto Mendoza-Londono^{2

4

5}, Elena Pope^{3

5}, Ted Young^{6

7}, Christian R Marshall^{1

6

7}, Gregory Costain^{1

2

4

5}, Irene Lara-Corrales^{3

5}, Yiming Wang^{1

2

5}

Affiliations

¹ Genetics and Genome Biology Program, Peter Gilgan Centre for Research and Learning, Toronto, ON, Canada.
² Division of Clinical and Metabolic Genetics, The Hospital for Sick Children, Toronto, ON, Canada.
³ Division of Dermatology, The Hospital for Sick Children, Toronto, ON, Canada.
⁴ Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
⁵ Department of Paediatrics, University of Toronto, Toronto, ON, Canada.
⁶ Division of Genome Diagnostics, The Hospital for Sick Children, Toronto, ON, Canada.
⁷ Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.

Neta Pipko et al. Br J Dermatol. 2025.

. 2025 Apr 28;192(5):933-935.

doi: 10.1093/bjd/ljae462.

¹ Genetics and Genome Biology Program, Peter Gilgan Centre for Research and Learning, Toronto, ON, Canada.
² Division of Clinical and Metabolic Genetics, The Hospital for Sick Children, Toronto, ON, Canada.
³ Division of Dermatology, The Hospital for Sick Children, Toronto, ON, Canada.
⁴ Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
⁵ Department of Paediatrics, University of Toronto, Toronto, ON, Canada.
⁶ Division of Genome Diagnostics, The Hospital for Sick Children, Toronto, ON, Canada.
⁷ Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.

No abstract available

Conflict of interest statement

Conflicts of interest: The authors declare they have no conflicts of interest.