Amanita-Induced Hepatitis
- PMID: 39583449
- PMCID: PMC11585366
- DOI: 10.7759/cureus.72325
Amanita-Induced Hepatitis
Abstract
The consumption of wild mushrooms can be associated with poisoning, particularly with species containing hepatotoxic toxins such as amatoxin, present in more than 35 species. We present a case of Amanita-induced hepatitis in a 73-year-old man after ingestion of wild mushrooms. He presented to the emergency department (ED) with severe diarrhea, intense abdominal pain, and vomiting, with onset approximately six hours after ingestion of wild mushrooms. He developed acute liver injury but never developed hepatic encephalopathy. His clinical course was favorable, with complete recovery of liver function. The diagnosis of Amanita-induced toxic hepatitis is based on clinical observations. Early diagnosis and treatment are fundamental factors in the prognosis of these patients.
Keywords: amatoxin; hepatitis; liver failure; mushrooms; n-acetylcysteine.
Copyright © 2024, Ribeiro et al.
Conflict of interest statement
Human subjects: Consent for treatment and open access publication was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.
References
-
- Amatoxin-containing mushroom poisonings: species, toxidromes, treatments, and outcomes. Diaz JH. Wilderness Environ Med. 2018;29:111–118. - PubMed
-
- Toward the antioxidant and chemical characterization of mycorrhizal mushrooms from northeast Portugal. Reis FS, Heleno SA, Barros L, Sousa MJ, Martins A, Santos-Buelga C, Ferreira IC. J Food Sci. 2011;76:0–30. - PubMed
-
- EASL Clinical Practical Guidelines on the management of acute (fulminant) liver failure. Wendon J, Cordoba J, Dhawan A, et al. J Hepatol. 2017;66:1047–1081. - PubMed
-
- Amanita phalloides poisoning: mechanisms of toxicity and treatment. Garcia J, Costa VM, Carvalho A, Baptista P, de Pinho PG, de Lourdes Bastos M, Carvalho F. Food Chem Toxicol. 2015;86:41–55. - PubMed
Publication types
LinkOut - more resources
Full Text Sources