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. 2025 Feb;37(2):e14968.
doi: 10.1111/nmo.14968. Epub 2024 Nov 25.

Variation of Stomach Shapes in Gastric Emptying Scintigraphy: Correlation With Gastric Emptying Results, Body Weight, and Symptoms

Susie O Lee  1   2 , Remy Arwani  1   2 , Shelby McNeilly  1   2 , Samantha Kunkel  1   2 , Simin Dadparvar  1   2 , Alan H Maurer  1   2 , Henry P Parkman  1   2
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Variation of Stomach Shapes in Gastric Emptying Scintigraphy: Correlation With Gastric Emptying Results, Body Weight, and Symptoms

Susie O Lee et al. Neurogastroenterol Motil. 2025 Feb.

Abstract

Background: Although different gastric shapes are encountered in gastric emptying scintigraphy (GES), it is not known whether gastric shape is related to gastric emptying (GE) or symptoms.

Aim: To investigate different stomach shapes observed during GES and examine their associations with GE, body weight, and gastrointestinal (GI) symptoms.

Methods: This was a retrospective review of GES studies performed at our institution. Patients with prior gastric surgery were excluded. A classification of gastric shapes included: crescentic, J-shaped, reversed-L, cylindrical, and bag-like. Gastric shapes were correlated with GE, BMI, and GI symptoms using PAGI-SYM.

Results: 397 GES studies were reviewed (317 females, age 40.0 ± 20.3 years, BMI 27.8 ± 13.8 kg/m2). Gastric shapes were: 41.8% crescentic/comma-shaped, 34.0% J-shaped, 19.9% reversed L-shape, 2.8% cylindrical, and 1.5% bag-like. BMI was highest in crescentic/comma-shaped stomachs (30.1 ± 12.4 kg/m2) and lowest in bag-like stomachs (25.2 ± 9.9 kg/m2; p = 0.022). Delayed GE was most pronounced in bag-like stomachs (34.4 ± 33.1% retention at 4 h) and lowest in reversed-L shape (10.3 ± 15.6% retention at 4 h; p = 0.008). Regurgitation severity was greatest in bag-like stomachs (2.2 ± 1.5) compared to milder symptoms in reversed-L shape (1.3 ± 1.4; p = 0.029). Heartburn severity was increased in bag-like stomachs (2.3 ± 1.6) while patients with cylindrical stomachs reported least heartburn severity (1.1 ± 1.3; p = 0.11).

Conclusions: A classification system based on five gastric shapes observed during GES showed that crescent-shaped stomach was the most common shape and correlated with higher BMIs. Delayed GE was most pronounced in bag-like stomachs and lowest in reversed-L stomachs. Regurgitation and heartburn severity were greatest in bag-like stomachs with milder symptoms in reversed-L stomachs. Thus, gastric shape during GES is associated with gastric emptying, BMI, and symptom severity.

Keywords: gastric emptying scintigraphy; gastroparesis; stomach shape.

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References

    1. P. Vijayvargiya, S. Jameie‐Oskooei, M. Camilleri, V. Chedid, P. J. Erwin, and M. H. Murad, “Association Between Delayed Gastric Emptying and Upper Gastrointestinal Symptoms: A Systematic Review and Meta‐Analysis,” Erratum in: Gut 68 (2019): 804–813.
    1. F. Burdan, I. Rozylo‐Kalinowska, J. Szumilo, et al., “Anatomical Classification of the Shape and Topography of the Stomach,” Surgical and Radiologic Anatomy 34 (2012): 171–178.
    1. A. M. Karnul and C. K. Murthy, “A Study of Variations of the Stomach in Adults and Growth of the Fetal Stomach,” Cureus 14 (2022): e28517.
    1. K. Yesupadam, K. N. Geetha Devi, and V. V. Lakshmi, “A Cadaveric Study for Structural Variations of the Stomach,” International Journal of Research in Medical Sciences 4 (2016): 3473–3478.
    1. G. Tougas, E. Y. Eaker, T. L. Abell, et al., “Assessment of Gastric Emptying Using a Low Fat Meal: Establishment of International Control Values,” American Journal of Gastroenterology 95 (2000): 1456–1462.

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